DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4408 and Cpa6

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_038965675.1	Gene:	Cpa6 / 312913	RGDID:	1311764	Length:	290	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	101/289 - (34%)
Similarity:	158/289 - (54%)	Gaps:	23/289 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 LAETHPEVLLV-ELGVSAQGRPILGVQIAFDNE-NRTTVFVESGIHAREWIAPATATYIIDQ--L 252
            |.:|.|.::.| .:|.|.:||.:|.:|:...:: .:..|:::.||||||||.||...:.:.:  |
  Rat     4 LNQTQPGLVRVFPIGRSFEGRSLLIIQLGRKSQVYKRAVWIDCGIHAREWIGPAFCQWFVKEAIL 68

  Fly   253 VNSKDSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRKNRALFG--ICRGVDLNRNFPFHWNV 315
            ....|.|::.:.....:||.|.:|.|||.:::..||.|||.|:...  .|||||.|||:...|..
  Rat    69 TYKTDPAMRKMLNHLYFYIMPVLNVDGYHFSWTHDRFWRKTRSRNSKFHCRGVDANRNWKVKWCD 133

  Fly   316 TGASGDPCRYDYSGPSAASEVETQRMIEFIR-HRVESERIRTFISLHSYSQMIMFPYGHSAERVD 379
            .|||.|||...|.||...||.|.:.:..|:| ||   :|||.::|.|:|:||:::||.:....:.
  Rat   134 EGASADPCDDTYCGPFPESEPEVKAVANFLRKHR---KRIRAYLSFHAYAQMLLYPYSYKHATIP 195

  Fly   380 NYHDLTDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYELR-----G 439
            |:..:......|...::.|.|..|:.|...:|:|.|||.|.|||: :..||.:|::|||     |
  Rat   196 NFSCVEFAAHKAVKALRSVHGIRYRHGPASQTLYVSSGNSMDWAY-KNGIPYSFAFELRDTGYFG 259

  Fly   440 PADSEDLFILSAKEIEPTAAEAFASIQTI 468
                   |:|....|:||..|...:::.|
  Rat   260 -------FLLPEMLIKPTCTETMLAVKNI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	101/289 (35%)
Cpa6	XP_038965675.1	Peptidase_M14_like	1..289	CDD:416253	101/289 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351686
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.750