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Protein Alignment CG4408 and CPA2

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	396	Identity:	122/396 - (30%)
Similarity:	215/396 - (54%)	Gaps:	25/396 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 VELASEEHVRLFQALEQASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNF 153
            ::|.::||::|           .|......||:...:.|....|......:.|..:.:.::..:.
Human    42 LQLEAQEHLQL-----------DFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDV 95

  Fly   154 QALIDANYLEVA--PEDTKPEEFDWKRYHPLESINAWLKKLAETHPE-VLLVELGVSAQGRPILG 215
            |.|:|....|:.  ....:...|::..||.||.|:..:..|...||. |..|.:|.|.:.||:..
Human    96 QVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNV 160

  Fly   216 VQIAFDNENRTTVFVESGIHAREWIAPATATYIIDQLVN--SKDSAVQALARSQRWYIFPTVNPD 278
            ::.:...: :..:::::|||||||:..|||.:..:::|:  .||.::.::..:...::.|..|||
Human   161 LKFSTGGD-KPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPD 224

  Fly   279 GYQYTFKGDRMWRKNRALF--GICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRM 341
            ||.::...:|||||.|:..  .:|.|||.|||:...:...|||.:||...|.||||.||||.:.:
Human   225 GYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSI 289

  Fly   342 IEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSG 406
            ::||:   ...:::.||:||||||::|||||:...::|::.:|:::.:.||..::.:.|..||.|
Human   290 VDFIK---SHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVG 351

  Fly   407 SIYETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTIVQE 471
            .|...||.:||||.||:: ...|..:|::|||......  |:|.|::|.|||.|.:..::.|::.
Human   352 PICSVIYQASGGSIDWSY-DYGIKYSFAFELRDTGRYG--FLLPARQILPTAEETWLGLKAIMEH 413

  Fly   472 AGKRGY 477
            .....|
Human   414 VRDHPY 419

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.