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Protein Alignment CG4408 and CPA1

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens

Alignment Length:	402	Identity:	115/402 - (28%)
Similarity:	209/402 - (51%)	Gaps:	15/402 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 RIYQVELASEEHVRLFQALEQASD-SCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRV 148
            ::.::.:|.|..|:..:.||.... ...|......||..:.:.|....:......:.|:.:::..
Human    24 QVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYET 88

  Fly   149 LNYNFQALIDANYLEV---APEDTKPEEFDWKRYHPLESINAWLKKLAETHPE-VLLVELGVSAQ 209
            :..:.|:|:|....::   .......:.|::..||.||.|..:|..|...:|. |..:::|.:.:
Human    89 MIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYE 153

  Fly   210 GRPILGVQIAFDNENRTTVFVESGIHAREWIAPATATYIIDQLVN--SKDSAVQALARSQRWYIF 272
            ||||..::.:.....|..:::::|||:|||:..|:..:...::..  .:|:|..|:..:...::.
Human   154 GRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLE 218

  Fly   273 PTVNPDGYQYTFKGDRMWRKNRA--LFGICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASE 335
            ...||||:.:|...:|||||.|:  ...:|.|||.|||:...:.::|||.:||...|.|..|.||
Human   219 IVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSE 283

  Fly   336 VETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSG 400
            ||.:.:::|::   :...|:.|||:|||||::|:|||:..|.|.:..:|..:.|.|...:..:.|
Human   284 VEVKSIVDFVK---DHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYG 345

  Fly   401 RIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASI 465
            ..:..|||.:.||.:||.:.||.:.| .|..:|::|||......  |:|.|.:|.|||.|.:.::
Human   346 TKFNYGSIIKAIYQASGSTIDWTYSQ-GIKYSFTFELRDTGRYG--FLLPASQIIPTAKETWLAL 407

  Fly   466 QTIVQEAGKRGY 477
            .||::......|
Human   408 LTIMEHTLNHPY 419

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.