DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4408 and cpa3

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_031758725.1	Gene:	cpa3 / 100494117	XenbaseID:	XB-GENE-853724	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	411	Identity:	131/411 - (31%)
Similarity:	221/411 - (53%)	Gaps:	26/411 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 TAADSVQAR--YDHTRIYQVELASEEHVRLFQALEQA-------SDSCSFMGHARQPGQKLTIMV 127
            :||.:|.|:  :...::::.:|.:|.||.|...:::|       .|:...|    .|..:....|
Frog    15 SAASAVLAKQTFHGDKVFRAKLQTEGHVALIHKIKEAIKLDFWHPDTADRM----VPHTEADFHV 75

  Fly   128 TGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEVAPEDTKPEEFDWKRYHPLESINAWLKKL 192
            ...:......|:...:|.:.||.::.|..|:|.    .....|.:...:.:|:..|.|..|..||
Frog    76 HSDQADSVQILLQQNSVPYEVLFHDLQEGIEAQ----LNNTKKSKRHSYTKYNTWEKIVEWTSKL 136

  Fly   193 AETHPE-VLLVELGVSAQGRPILGVQIAFDNENRTTVFVESGIHAREWIAPATATYIIDQLVNSK 256
            .:.:|. |..:::|.|.:|||:..:|:...:.....:|::.||||||||:||...:.:.:|:..|
Frog   137 TKKYPNLVQRIDIGKSVEGRPMYVLQVGNPDSATKAIFMDCGIHAREWISPAFCQWFVKELIKGK 201

  Fly   257 DSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRKNRALF--GICRGVDLNRNFPFHWNVTGAS 319
            :: ::.|.:|..:||.|..|.|||.:|:..||||||||:..  ..|.|.||||||...|...|:|
Frog   202 NN-IRELVKSLTFYILPVFNIDGYVWTWTEDRMWRKNRSPSEDAKCVGTDLNRNFNISWCDIGSS 265

  Fly   320 GDPCRYDYSGPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDL 384
            .:||...|.|.:|.||:||:.:..|||..|:|  |:.:||.||:|||::||:.::.|...::.:|
Frog   266 DEPCSEIYCGAAAESEIETKNVASFIRSHVDS--IKAYISFHSFSQMLLFPFSYTYELAPDHKEL 328

  Fly   385 TDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFIL 449
            .:|.|.|..:::.:.|..|..|....||||::|.|.|||: .|.|..:|::|||.  :.:..|:|
Frog   329 DEIAKGAVAELQGLYGTSYTYGPSASTIYPTAGSSDDWAY-SLGIKYSFTFELRD--EGKKGFLL 390

  Fly   450 SAKEIEPTAAEAFASIQTIVQ 470
            ...:|:.|..|...::..|.:
Frog   391 PQSQIKATCQETTLAVAYIAK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	16/77 (21%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	109/295 (37%)
cpa3	XP_031758725.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920