DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4408 and cpo

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001139101.1	Gene:	cpo / 100005630	ZFINID:	ZDB-GENE-070619-6	Length:	363	Species:	Danio rerio

Alignment Length:	307	Identity:	106/307 - (34%)
Similarity:	180/307 - (58%)	Gaps:	14/307 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 EEFDWKRYHPLESINAWLKKLAETHPEVL-LVELGVSAQGRPILGVQIAFDNEN-RTTVFVESGI 234
            :.:|:.:||.::.|:||:.::...:|:|: .:..|.:.:.|.|..::|.|.:.. :..::::.||
Zfish    28 KSYDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTTPKKAIWMDCGI 92

  Fly   235 HAREWIAPATATYIIDQLVNS--KDSAVQALARSQRWYIFPTVNPDGYQYTF--KGDRMWRKNRA 295
            |||||||||...:.:.:::.|  .||.|..|.::..:||.|.:|.|||.|::  ...|:|||:|:
Zfish    93 HAREWIAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRKSRS 157

  Fly   296 LF---GICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESERIRTF 357
            ..   ..|.|.||||||..:|.:.|.|.:.|...|:|.:|.||.|.:.:.:|:  ......:..:
Zfish   158 PCHENSTCSGTDLNRNFYANWGMVGISRNCCSEVYNGATALSEPEAEAVTDFL--GAHQNHLLCY 220

  Fly   358 ISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGSKDW 422
            :::|||.|:|:.||||......||.:|.::|..||..||.|.|:.||.||..:.:||:||.|:|:
Zfish   221 LTIHSYGQLILVPYGHPNISAPNYDELMEVGLAAAKAIKAVHGKSYKVGSSPDVLYPNSGSSRDF 285

  Fly   423 AHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTIV 469
            |. .:.||.:|::|||.  :.:..|||...:|:||..||:....:|:
Zfish   286 AR-LIGIPYSFTFELRD--EGQHGFILPEDQIQPTCQEAYEGAMSII 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	105/300 (35%)
cpo	NP_001139101.1	M14_CP_A-B_like	35..332	CDD:199844	105/300 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593477
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750