DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pnt and Ets96B

DIOPT Version :9

Sequence 1:	NP_524461.2	Gene:	pnt / 42757	FlyBaseID:	FBgn0003118	Length:	718	Species:	Drosophila melanogaster
Sequence 2:	NP_996290.1	Gene:	Ets96B / 42952	FlyBaseID:	FBgn0039225	Length:	640	Species:	Drosophila melanogaster

Alignment Length:	489	Identity:	123/489 - (25%)
Similarity:	193/489 - (39%)	Gaps:	108/489 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 GNSFESATTASVCGS------------------DHQVAN------YPNETHA-------NSNNSS 293
            |:|.....:||:|..                  .||:.:      .|..|.|       .|....
  Fly   163 GSSSAGGASASLCNDLTRESSWYAHHHHHHHHHHHQLPDELVMYATPTPTPAIGKFGLDTSTEGY 227

  Fly   294 INSRLSMDYVTSAGNSDNKNFH--RATPHSHNGYNTSNTHDRIN------NSTPPQ--QQQSQQP 348
            :|:|.::: |....:....:|.  .|..|.|| :...:.|...:      .|:||.  .::|.:.
  Fly   228 LNARYNVN-VKGVRHDRTSSFFDIPAVTHPHN-HPHPHPHPHPHPYCYRFPSSPPAGILKKSDEE 290

  Fly   349 TVNGSGSASSNNNNSMLPPAVQQSNNENNNTSSSNTNNSSNNNNNSGGSNNSNAGSNNNNNNNNN 413
            ..:.:...|..::....|...:..:.::..|::.............         ........:.
  Fly   291 ATSAAVYCSDVSSGQHFPHHTKIEHADSTTTAAQQQQQQQEQQQQQ---------QQQQQQQQHQ 346

  Fly   414 INFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHLAAYGGGSGSGPTGGR 478
            .....|||:..||       .:.:.|.:|.....|...|.|:    |.|.|:....|.:...
  Fly   347 QQLQQAAALHPHH-------HHSHHGHHGHQQAEQQALTHLT----PLHAASAFKFSHTAVI--- 397

  Fly   479 SSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHDG 543
                  ..|..::|.|...||.|               |.:.:.|.|.|.....:.:..:..:|.
  Fly   398 ------SSSAVYATPSHYAHQQQ---------------TQSQSVYRDLSPTTLAAVSDADLKYDS 441

  Fly   544 YPPEFTPYDAQSFQSMGP---QPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFT 605
                 .||:| :..|..|   :|..:|...::.|......:.::.|:.       |:..|.....
  Fly   442 -----GPYNA-AISSTYPSALRPNVVDSTTSSDAELRLDQFYASNGIS-------TSSNGQAISQ 493

  Fly   606 GSGPIQLWQFLLELLLDKTCQ-SFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLR 669
            ..|.:||||||:.||.:.|.. |.|:|||.|.||||.:|:|||||||::||:|.|||:||||.||
  Fly   494 RRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLSRSLR 558

  Fly   670 YYYDKNIIHKTAGKRYVYRFVCD---LQNLV-GH 699
            |||:|.|:.|..|:|||||||||   |.|:. ||
  Fly   559 YYYEKGIMQKVNGERYVYRFVCDPDALFNMAYGH 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
pnt	NP_524461.2	ETS	609..693	CDD:197710	55/87 (63%)
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	55/85 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450443
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11849
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850