DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pnt and Etv2

DIOPT Version :9

Sequence 1:	NP_524461.2	Gene:	pnt / 42757	FlyBaseID:	FBgn0003118	Length:	718	Species:	Drosophila melanogaster
Sequence 2:	XP_038949886.1	Gene:	Etv2 / 361544	RGDID:	1310603	Length:	368	Species:	Rattus norvegicus

Alignment Length:	285	Identity:	102/285 - (35%)
Similarity:	128/285 - (44%)	Gaps:	76/285 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   431 PGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHL---AAYGGGS---GSGPTGGR--SSGGGGD-E 486
            |||......|: .|:..||..|  |:.|:|:..   |.:...|   .:||.|..  .||.||: :
  Rat   141 PGTSPSPFVGF-EGATGQNTAT--SAGGVPSWSHPPATWSTASWDCSAGPNGSTYWDSGLGGEAQ 202

  Fly   487 SDYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPY 551
            :||            :.|.| ||.|:...:|.|| |..:.|..|.|...          |.|...
  Rat   203 ADY------------KMSWG-GSAGSDYTTTWNS-GLQNCSIPFEGHQI----------PAFATP 243

  Fly   552 DAQSFQSMGPQPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFL 616
            ...|.||                             |:..|..|:..      ...|||||||||
  Rat   244 SKSSQQS-----------------------------DRATLTPYSKT------NHRGPIQLWQFL 273

  Fly   617 LELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTA 681
            ||||.|....|.|.|||:..||:|.||.||||.||.||.||.||||||||||||||.::|:.|:.
  Rat   274 LELLHDGARSSCIRWTGNNREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSG 338

  Fly   682 GKRYVYRF-----VCDLQNLVGHTP 701
            |::|.|||     |...|:.:||.|
  Rat   339 GRKYTYRFGGRVPVLACQDDMGHLP 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
pnt	NP_524461.2	ETS	609..693	CDD:197710	55/88 (63%)
Etv2	XP_038949886.1	ETS	266..348	CDD:197710	54/81 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920