Protein Alignment pnt and Fli1

DIOPT Version :10

• Sequence 1: NP_524461.2
• Gene: pnt / 42757
• FlyBaseID: FBgn0003118
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001017381.1
• Gene: Fli1 / 315532
• RGDID: 1309837
• Length: 452
• Species: Rattus norvegicus
• Alignment Length: 653
• Identity: 144/653 - (22%)
• Similarity: 185/653 - (28%)
• Gaps: 353/653 - (54%)

  Fly   130 SLSDISDHE--------ASLEVPTA------------------LPPLTPGTNRKVNEVLKASF-- 166
            :||.:||.:        |:..:|.|                  |||.....|:.|...:|..:
  Rat     8 ALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVRVNVKREYDH 72

  Fly   167 --ASWEK----EVQKCN------------------------------------ITKDPREWTEEH 189
              .|.|.    .|.|||                                    :..||..||:||
  Rat    73 MNGSRESPVDCSVSKCNKLVGGGEANPMNYNSYMDEKNGPPPPNMTTNERRVIVPADPTLWTQEH 137

  Fly   190 VIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAITPPFTGDILWEHLDILQKDCEKPN 254
            |..||.||..|:.|:.::...|..|.|:.:..:.||.||..|..:..::|..||..|:
  Rat   138 VRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMSKEDFLRATSLYNTEVLLSHLSYLR------- 195

  Fly   255 EDIVHGNSFESATTASVCGSDHQVANYPNETHANSNNSSINSRLSMDYVTSAGNSDNKNFHRATP 319
                     ||:..|
  Rat   196 ---------ESSLLA-------------------------------------------------- 201

  Fly   320 HSHNGYNTSNTHDRINNSTPPQQQQSQQPTVNGSGSASSNNNNSMLPPAVQQSNNENNNTSSSNT 384
                 |||                                                     .|:|
  Rat   202 -----YNT-----------------------------------------------------PSHT 208

  Fly   385 NNSSNNNNNSGGSNNSNAGSNNNNNNNNNINFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQN 449
            :.||..|                                   :||:|...:...||:....||
  Rat   209 DQSSRLN-----------------------------------VKEDPSYDSVRRGGWSNNMNS-- 236

  Fly   450 DPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASG 514
                              |.:.|.|.||..|.|...|.
  Rat   237 ------------------GINKSPPLGGAQSMGKNTEQ--------------------------- 256

  Fly   515 GSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPYDAQSFQSMGPQPTAMDQWGAAHAHQHPA 579
                                          .|:..||     |.:||..:.:         .:|
  Rat   257 ------------------------------RPQPDPY-----QILGPTSSRL---------ANP- 276

  Fly   580 AYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPD 644
                                      |||.|||||||||||.|....|.|:|.|...|||:||||
  Rat   277 --------------------------GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPD 315

  Fly   645 EVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDL----QNLVGHTPEELV 705
            |||||||.||:||.|||:||||.|||||||||:.|..||||.|:|  |.    |.|..|..|..:
  Rat   316 EVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF--DFHGIAQALQPHPTETSM 378

  Fly   706 AKY 708
            .||
  Rat   379 YKY 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879	25/70 (36%)
		ETS	609..693	CDD:197710	57/83 (69%)
Fli1	NP_001017381.1	SAM_PNT-FLI-1	114..204	CDD:188883	29/160 (18%)
		ETS	280..363	CDD:197710	58/84 (69%)