Protein Alignment pnt and ETV4

DIOPT Version :10

• Sequence 1: NP_524461.2
• Gene: pnt / 42757
• FlyBaseID: FBgn0003118
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001977.1
• Gene: ETV4 / 2118
• HGNCID: 3493
• Length: 484
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 99/292 - (33%)
• Similarity: 130/292 - (44%)
• Gaps: 88/292 - (30%)

  Fly   509 SGGASGGSTGNSNGY-----------LDSSSEFYGSYAGRNRFHDGYPPEFT----PYDAQSFQ- 557
            |.|.|....|  :||           ||....|.....||......|..:.:    ||..|||:
Human   165 SSGTSQPHPG--HGYLGEHSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQ 227

  Fly   558 -------SMGPQPTAMDQWGAAHAHQHPAA-----------------------YMSTLGLD---- 588
                   ....|| |:|| |..:.|::|.|                       |:.|.|..
Human   228 EYHDPLYEQAGQP-AVDQ-GGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSP 290

  Fly   589 -KGLLG-GY---------------------TTQGGV------PCFTGSGPIQLWQFLLELLLDKT 624
             .|.:| ||                     ..|.||      |.:...|.:||||||:.||.|.|
Human   291 GDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPT 355

  Fly   625 CQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 689
            ...||:|||.|.||||.:|:||||.|||:||:|.|||:||||.|||||:|.|:.|.||:||||:|
Human   356 NAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 420

  Fly   690 VCDLQNLVGHT-PEE----LVAKYDLKIEKKD 716
            ||:.:.|.... |:.    |.|::|..:.::|
Human   421 VCEPEALFSLAFPDNQRPALKAEFDRPVSEED 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
		ETS	609..693	CDD:197710	55/83 (66%)
ETV4	NP_001977.1	ETS_PEA3_N	8..339	CDD:461371	37/177 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..115
		ETS	341..424	CDD:197710	55/82 (67%)