DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pnt and ets-9

DIOPT Version :9

Sequence 1:	NP_524461.2	Gene:	pnt / 42757	FlyBaseID:	FBgn0003118	Length:	718	Species:	Drosophila melanogaster
Sequence 2:	NP_001371009.1	Gene:	ets-9 / 180702	WormBaseID:	WBGene00016865	Length:	225	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	58/213 - (27%)
Similarity:	87/213 - (40%)	Gaps:	67/213 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   548 FTPYDAQSFQSMGPQPTAMDQ----WGA-AHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGS 607
            || :|.:::..:.| ||..:.    |.. :.|.|.|.|                    ||.|..|
Worm    19 FT-HDVRTYPDISP-PTPTNSHIRCWAQFSIAQQLPCA--------------------VPSFPTS 61

  Fly   608 ---------------------GPIQLWQFLLELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWG 651
                                 ||.:|..||:.|.:::..:..:.|||:|.||.|.:.:.||:.||
Worm    62 LFPLPIMNDEPMTDDELVKMKGPSRLIGFLVHLAMNERARKALRWTGNGLEFVLVNKELVAKMWG 126

  Fly   652 IRKNKPK-MNYEKLSRGLRYYY------DKNIIH---KTAGKRYVYRFV----CDLQNLVGHTPE 702
            .||:..| |:|.||||.:|..|      ||||..   |...:.|.|.|.    .||.|   .|.:
Worm   127 NRKHNTKDMDYYKLSRAIREKYEKKDKADKNIKPGKLKKGTRTYSYVFTEHAYPDLMN---QTEK 188

  Fly   703 EL--VAKYDLKIEKKDVD 718
            ::  :.::...|.:|..|
Worm   189 DINFITRFAADIGQKYSD 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
pnt	NP_524461.2	ETS	609..693	CDD:197710	35/97 (36%)
ets-9	NP_001371009.1	Ets	86..>150	CDD:413392	26/63 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910