DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pnt and ast-1

DIOPT Version :9

Sequence 1:	NP_524461.2	Gene:	pnt / 42757	FlyBaseID:	FBgn0003118	Length:	718	Species:	Drosophila melanogaster
Sequence 2:	NP_001022326.1	Gene:	ast-1 / 173749	WormBaseID:	WBGene00020368	Length:	377	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	109/379 - (28%)
Similarity:	150/379 - (39%)	Gaps:	115/379 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 SNTHDRINNS---TPPQQQQSQQPTVNGSGSASSNNNNSMLP----PAVQQSNNE---NNNTSSS 382
            |:..|.|..|   |..|:||.||          ...:|:.||    |......|:   |....:.
Worm    25 SSDEDVIKYSAIQTIKQEQQQQQ----------QQQSNTALPSYNFPFFNGMQNDFPPNRMLYND 79

  Fly   383 NTNNSSNNNNNSGGSNNSNAGSNNNNNNNNNINFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNS 447
            ||...|.|::.:|.:.:::|.|:.|:.::.:.:        :.....|....:||......|||.
Worm    80 NTMQKSENDHFTGMNLSTSASSSGNSTSSKDQS--------RRQFYTESSNSSGNGAAATSGSNG 136

  Fly   448 QNDPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGA 512
            .:..|:..|......:.|:....||                     .::||
Worm   137 SSSSTESKSDVFNISMNAFAATPGS---------------------KSEDH-------------- 166

  Fly   513 SGGSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPYDAQSFQSMGPQPTAMDQWGAAHAHQH 577
                  |...:...||.:.|:....|......|   .||     |.:||....:       ||
Worm   167 ------NIPSFNMLSSYYTGALKLSNSTSFANP---DPY-----QILGPTSKNL-------AH-- 208

  Fly   578 PAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEFKLTD 642
                                       :|||..||||||||||.||.....|:|.|...||||.|
Worm   209 ---------------------------SGSGQTQLWQFLLELLSDKRYSEVITWEGTQGEFKLVD 246

  Fly   643 PDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQNL 696
            ||||||:||.||:||.|||:|:||.|||||||||:.|..||||.|:|  |.|.:
Worm   247 PDEVARKWGERKSKPNMNYDKMSRALRYYYDKNIMAKVHGKRYAYKF--DFQGI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
pnt	NP_524461.2	ETS	609..693	CDD:197710	54/83 (65%)
ast-1	NP_001022326.1	ETS	213..296	CDD:197710	55/84 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810