Protein Alignment bb8 and GDH1

DIOPT Version :10

• Sequence 1: NP_651140.1
• Gene: bb8 / 42756
• FlyBaseID: FBgn0039071
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_015020.3
• Gene: GDH1 / 854557
• SGDID: S000005902
• Length: 454
• Species: Saccharomyces cerevisiae
• Alignment Length: 526
• Identity: 139/526 - (26%)
• Similarity: 221/526 - (42%)
• Gaps: 111/526 - (21%)

  Fly    40 DPEFSEMVLYYYHKAAQTMEPALLKEMEKYPHMKPEERQARVTAILNLLGSVSTSVEVNFPIVRK 104
            :|||.:.    |.:...::|.:.|.|..      ||.|  :|..|:::...:     :.|.:..:
Yeast     3 EPEFQQA----YEEVVSSLEDSTLFEQH------PEYR--KVLPIVSVPERI-----IQFRVTWE 50

  Fly   105 N--GTYEIISGYRSHHVRHRLPLKGGIRYALDVNESEVKALAAIMTFKCACVNVPYGGSKGGICI 167
            |  |..|:..|||..:...:.|.|||:|:...||.|.:|.|.....||.:...:..||.|||:|:
Yeast    51 NDKGEQEVAQGYRVQYNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNSLTGLDMGGGKGGLCV 115

  Fly   168 DPKKYTVDELQTITRRYTMELLKRNMIGPGIDVPAPDVNTGPREMSWIVDQYQKTFGYKDINS-S 231
            |.|..:.:|::.|...:..||.:.  ||...||||.|:..|.||:.::...|:   .||  || .
Yeast   116 DLKGRSNNEIRRICYAFMRELSRH--IGQDTDVPAGDIGVGGREIGYLFGAYR---SYK--NSWE 173

  Fly   232 AIVTGKPVHNGGINGRHSATGRGVWKAGDLFLKDKEWMD-LLKWKTGWKDKTVIVQGFGNVGSFA 295
            .::|||.::.||...|..|||.|      |....:..:| ....|..::.|.|.:.|.|||..:|
Yeast   174 GVLTGKGLNWGGSLIRPEATGYG------LVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYA 232

  Fly   296 AKYVHEAGAKVIGIKEFDVSLVNKDGIDINDLFEYTEEKKTIKG-------YPKAQESKEDLL-- 351
            |..|.|.|..|:.:.:....::::.||....:.:.:..|...|.       |....|:|...:
Yeast   233 ALKVIELGGTVVSLSDSKGCIISETGITSEQVADISSAKVNFKSLEQIVNEYSTFSENKVQYIAG 297

  Fly   352 ------VAETDILMPCATQKVITTDNAKDIKA---KLILEGANGPTTPSGEKILL---------- 397
                  |.:.||.:|||||..::.:.||.:.|   |.|.||:|..:||  |.|.:
Yeast   298 ARPWTHVQKVDIALPCATQNEVSGEEAKALVAQGVKFIAEGSNMGSTP--EAIAVFETARSTATG 360

  Fly   398 -DKGVLLVPDLYCNAGGVTVSYFEYLKNINHVSYGKMNSKSTSELIIELMNSINESLHECPDSQL 461
             .:.|...|....|.|||.||..|..:|...:::       |||.:
Yeast   361 PSEAVWYGPPKAANLGGVAVSGLEMAQNSQRITW-------TSERV------------------- 399

  Fly   462 PNICPNKKLKRIQ-QCTTEADIVDSALQTVMESAARGIKEMAHKFELCNDLRRAAYVWSSFKIFQ 525
                 :::||||. .|..|.  :|.|            |:.....::...|.:.|.:.|..|:..
Yeast   400 -----DQELKRIMINCFNEC--IDYA------------KKYTKDGKVLPSLVKGANIASFIKVSD 445

  Fly   526 AMESSG 531
            ||...|
Yeast   446 AMFDQG 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bb8	NP_651140.1	GdhA	40..532	CDD:440103	139/526 (26%)
GDH1	NP_015020.3	PRK09414	3..451	CDD:181834	138/524 (26%)