Protein Alignment bb8 and GDH2

DIOPT Version :9

• Sequence 1: NP_651140.1
• Gene: bb8 / 42756
• FlyBaseID: FBgn0039071
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_010066.1
• Gene: GDH2 / 851311
• SGDID: S000002374
• Length: 1092
• Species: Saccharomyces cerevisiae
• Alignment Length: 539
• Identity: 119/539 - (22%)
• Similarity: 198/539 - (36%)
• Gaps: 146/539 - (27%)

  Fly    48 LYYYHKAAQTMEPAL-LKEMEKY-PHMKPEERQARVT----------AILNLLGSVSTSV-EVNF 99
            ::|||.:.:.||..| .:.:||. |....:|.:|.:.          .||..|...:.|: :.||
Yeast   467 IHYYHNSTKDMEKTLSFQRLEKVEPFKNDQEFEAYLNKFIPNDSPDLLILKTLNIFNKSILKTNF 531

  Fly   100 PIVRK----------------------NGTYEIISG-YRSHHVRHRLPLKGGIRYA-------LD 134
            .|.||                      .|.:.::.. ::..|:|.|...:||||..       .|
Yeast   532 FITRKVAISFRLDPSLVMTKFEYPETPYGIFFVVGNTFKGFHIRFRDIARGGIRIVCSRNQDIYD 596

  Fly   135 VNESEV----KALAAIMTFKCACVNVPYGGSKGGICIDPKKYTVDELQTITRRYTMELLKRNMIG 195
            :|...|    ..||:....|..  ::|.|||||.|.::|.....|:......:|         :.
Yeast   597 LNSKNVIDENYQLASTQQRKNK--DIPEGGSKGVILLNPGLVEHDQTFVAFSQY---------VD 650

  Fly   196 PGIDVPAPD------VNTGPREMSWIVDQYQKTFGYKDINSS-----------AIVTGKPVHNGG 243
            ..||:...|      ||..|:|........:.|.|:.|..::           :.:|||....||
Yeast   651 AMIDILINDPLKENYVNLLPKEEILFFGPDEGTAGFVDWATNHARVRNCPWWKSFLTGKSPSLGG 715

  Fly   244 I-NGRHSATGRGVWKAGDLFLKDKEWMDL-----LKWKTGWKDKTVIVQGFGNVGSFAAKYVHEA 302
            | :..:..|..||....:   |..|.::|     .|::||..|        |::||... .:...
Yeast   716 IPHDEYGMTSLGVRAYVN---KIYETLNLTNSTVYKFQTGGPD--------GDLGSNEI-LLSSP 768

  Fly   303 GAKVIGIKEFDVSLVNKDGIDINDLFEYTEEKKTIKGYPKAQESKEDLLVA-------------- 353
            ....:.|.:....|.:..|:|.::|.....|:|.|..:..::.|.....|:
Yeast   769 NECYLAILDGSGVLCDPKGLDKDELCRLAHERKMISDFDTSKLSNNGFFVSVDAMDIMLPNGTIV 833

  Fly   354 -------------------ETDILMPCATQ-KVITTDN------AKDIKAKL--ILEGANGPTTP 390
                               ..||.:||..: ..||.:|      .|..|.|:  |:||||...|.
Yeast   834 ANGTTFRNTFHTQIFKFVDHVDIFVPCGGRPNSITLNNLHYFVDEKTGKCKIPYIVEGANLFITQ 898

  Fly   391 SGEKILLDKGVLLVPDLYCNAGGVTVSYFEYLKNIN-------HVSYGKMNSKSTS---ELIIEL 445
            ..:..|.:.|.:|..|...|.||||.|..|.|.::.       |...|.::.:.::   ..::|:
Yeast   899 PAKNALEEHGCILFKDASANKGGVTSSSMEVLASLALNDNDFVHKFIGDVSGERSALYKSYVVEV 963

  Fly   446 MNSINESLHECPDSQLPNI 464
            .:.|.::. |....||.|:
Yeast   964 QSRIQKNA-ELEFGQLWNL 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bb8	NP_651140.1	GdhA	72..532	CDD:223411	110/513 (21%)
		ELFV_dehydrog_N	95..221	CDD:280903	36/166 (22%)
		NAD_bind_1_Glu_DH	242..517	CDD:133445	62/281 (22%)
GDH2	NP_010066.1	Bac_GDH	1..1092	CDD:421780	119/539 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344915
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740