Protein Alignment bb8 and GDH3

DIOPT Version :9

• Sequence 1: NP_651140.1
• Gene: bb8 / 42756
• FlyBaseID: FBgn0039071
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_009339.1
• Gene: GDH3 / 851237
• SGDID: S000000058
• Length: 457
• Species: Saccharomyces cerevisiae
• Alignment Length: 489
• Identity: 135/489 - (27%)
• Similarity: 212/489 - (43%)
• Gaps: 88/489 - (17%)

  Fly    40 DPEFSEMVLYYYHKAAQTMEPALLKEMEKYPHMKPEERQARVTAILNLLGSVSTSVEVNFPIVRK 104
            :|||.:.    |.:...::|.:  |..||:|..|         .:|.::......::........
Yeast     4 EPEFQQA----YDEIVSSVEDS--KIFEKFPQYK---------KVLPIVSVPERIIQFRVTWEND 53

  Fly   105 NGTYEIISGYRSHHVRHRLPLKGGIRYALDVNESEVKALAAIMTFKCACVNVPYGGSKGGICIDP 169
            ||..|:..|||......:.|.|||:|:...||.|.:|.|.....||.|...:..||.|||:|:|.
Yeast    54 NGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDL 118

  Fly   170 KKYTVDELQTITRRYTMELLKRNMIGPGIDVPAPDVNTGPREMSWIVDQYQKTFGYKDINS-SAI 233
            |..:.:|::.|...:..||.:.  ||...||||.|:..|.||:.::...|:   .||  || ..:
Yeast   119 KGKSDNEIRRICYAFMRELSRH--IGKDTDVPAGDIGVGGREIGYLFGAYR---SYK--NSWEGV 176

  Fly   234 VTGKPVHNGGINGRHSATGRGVWKAGDLFLKDKEWMD-LLKWKTGWKDKTVIVQGFGNVGSFAAK 297
            :|||.::.||...|..|||.|      |....:..:| ....|..::.|.|.:.|.|||..:||.
Yeast   177 LTGKGLNWGGSLIRPEATGFG------LVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAAL 235

  Fly   298 YVHEAGAKVIGIKEFDVSLVNKDGI---DINDL------FEYTEEKKTIKGYPKAQESKEDLL-- 351
            .|.|.|..|:.:.:....::::.||   .|:|:      |:..||  .:..|....|||...:
Yeast   236 KVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAKIRFKSLEE--IVDEYSTFSESKMKYVAG 298

  Fly   352 ------VAETDILMPCATQKVITTDNAKDIKA---KLILEGANGPTTPSGEKIL---------LD 398
                  |:..||.:|||||..::.|.||.:.|   |.:.||||..:||....:.         ..
Yeast   299 ARPWTHVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETARSTATNAK 363

  Fly   399 KGVLLVPDLYCNAGGVTVSYFEYLKNINHVSYGKMNSKSTSELIIELMNSINESLHECPDSQLPN 463
            ..|...|....|.|||.||..|..:|...|::       |:|.:               |.:|..
Yeast   364 DAVWFGPPKAANLGGVAVSGLEMAQNSQKVTW-------TAERV---------------DQELKK 406

  Fly   464 I---CPNKKLKRIQQCTTEADIVDSALQTVMESA 494
            |   |.|..::..|:.:||.:  .:.|.::::.|
Yeast   407 IMINCFNDCIQAAQEYSTEKN--TNTLPSLVKGA 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bb8	NP_651140.1	GdhA	72..532	CDD:223411	126/457 (28%)
		ELFV_dehydrog_N	95..221	CDD:280903	42/125 (34%)
		NAD_bind_1_Glu_DH	242..517	CDD:133445	75/286 (26%)
GDH3	NP_009339.1	PRK09414	4..454	CDD:181834	135/489 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	79	1.000	Domainoid score	I2038
eggNOG	1	0.900	-	-		E1_COG0334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I1193
Isobase	1	0.950	-	0.917438	Normalized mean entropy	S1271
OMA	1	1.010	-	-		QHG54967
OrthoFinder	1	1.000	-	-		FOG0001473
OrthoInspector	1	1.000	-	-		mtm9211
orthoMCL	1	0.900	-	-		OOG6_100455
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R306
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.710