Protein Alignment bb8 and gdh1

DIOPT Version :9

• Sequence 1: NP_651140.1
• Gene: bb8 / 42756
• FlyBaseID: FBgn0039071
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_588184.1
• Gene: gdh1 / 2539147
• PomBaseID: SPCC622.12c
• Length: 451
• Species: Schizosaccharomyces pombe
• Alignment Length: 534
• Identity: 134/534 - (25%)
• Similarity: 224/534 - (41%)
• Gaps: 123/534 - (23%)

  Fly    35 VETDKDPEFSEMVLYYYHKAAQTMEPALLKEMEKYPHMKPEERQARVTAILNLLGSVSTSVEVNF 99
            :.|..:|||.:.    |.:...::|.:  |..|.:|.:|      ||..|:::...|     :.|
pombe     1 MSTPYEPEFQQA----YKEIVGSIESS--KLFEVHPELK------RVLPIISIPERV-----LEF 48

  Fly   100 PIVRKN--GTYEIISGYRSHHVRHRLPLKGGIRYALDVNESEVKALAAIMTFKCACVNVPYGGSK 162
            .:..::  |...:.:|||........|.|||:|:...||.|.:|.|.....||.|...:|.||.|
pombe    49 RVTWEDDKGNCRVNTGYRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLPMGGGK 113

  Fly   163 GGICIDPKKYTVDELQTITRRYTMELLKRNMIGPGIDVPAPDVN-TGPREMSWIVDQYQKTFG-Y 225
            ||...|||..:.:|::..::.:..:|.:  .|||..||||.|:. ||     ::|   ...|| |
pombe   114 GGSDFDPKGKSDNEIRRFSQAFMRQLFR--YIGPQTDVPAGDIGVTG-----FVV---MHMFGEY 168

  Fly   226 KDINS--SAIVTGKPVHNGGINGRHSATGRGVWKAGDLFLKDKEWMDLLKWKT----GWKDKTVI 284
            |.:.:  |.:||||.:..||.|.|..|||.||    ..::|     .:::.:|    ..|.|.|.
pombe   169 KRLRNEYSGVVTGKHMLTGGSNIRPEATGYGV----VYYVK-----HMIEHRTKGAETLKGKRVA 224

  Fly   285 VQGFGNVGSFAAKYVHEAGAKVIGIKEFDVSLVNK--DGI---DINDLFEYTEEKKTI------- 337
            :.|.|||..:||....:.||.|..|.:....|:.|  :|:   :|:::....|::.:|
pombe   225 ISGSGNVAQYAALKCIQEGAIVKSISDSKGVLIAKTAEGLVPEEIHEIMALKEKRASIADSASLC 289

  Fly   338 KGYPKAQESKEDLLVAETDILMPCATQKVITTDNAKDI---KAKLILEGANGPTTPSGEKIL--- 396
            |.:.....::....|.|.||.:|||||..::.:.|..:   ..:.:.||:|..::....::.
pombe   290 KKHHYIAGARPWTNVGEIDIALPCATQNEVSGEEAAALIKQGCRYVAEGSNMGSSAEAVEVFEKS 354

  Fly   397 --LDKGVLLVPDLYCNAGGVTVSYFEYLKNINHVSYGKMNSKSTSELIIELMNSINESLHECPDS 459
              ..:|..|.|....|||||.||..|..:|....::
pombe   355 RASGEGCWLAPGKAANAGGVAVSGLEMAQNAQFSTW----------------------------- 390

  Fly   460 QLPNICPNKKLKRIQQCTTEADIVDSALQTVMESAARGIKEMAHKFELCN-------DLRRAAYV 517
                              |.|: ||:.|..:|::......::|.|:  |:       .|...|.:
pombe   391 ------------------THAE-VDAKLAGIMQNIFEQSTDVASKY--CDSGSNNIPSLVDGANI 434

  Fly   518 WSSFKIFQAMESSG 531
            ....|:..||::.|
pombe   435 AGFLKVATAMQAVG 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bb8	NP_651140.1	GdhA	72..532	CDD:223411	125/497 (25%)
		ELFV_dehydrog_N	95..221	CDD:280903	40/128 (31%)
		NAD_bind_1_Glu_DH	242..517	CDD:133445	67/305 (22%)
gdh1	NP_588184.1	PRK09414	4..448	CDD:181834	132/529 (25%)
		ELFV_dehydrog_N	42..170	CDD:280903	44/142 (31%)
		NAD_bind_2_Glu_DH	180..449	CDD:133455	74/328 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	75	1.000	Domainoid score	I2482
eggNOG	1	0.900	-	-		E1_COG0334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I1551
OMA	1	1.010	-	-		QHG54967
OrthoFinder	1	1.000	-	-		FOG0001473
OrthoInspector	1	1.000	-	-		otm47168
orthoMCL	1	0.900	-	-		OOG6_100455
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R306
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.760