Protein Alignment bb8 and Glud1

DIOPT Version :9

• Sequence 1: NP_651140.1
• Gene: bb8 / 42756
• FlyBaseID: FBgn0039071
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_032159.1
• Gene: Glud1 / 14661
• MGIID: 95753
• Length: 558
• Species: Mus musculus
• Alignment Length: 529
• Identity: 236/529 - (44%)
• Similarity: 344/529 - (65%)
• Gaps: 22/529 - (4%)

  Fly    11 GIYPLMPRQVLKRSAHQVPEKLKKVETDKDPEFSEMVLYYYHKAAQTMEPALLKEMEKYPHMKPE 75
            |:.|:..|...:.:|          :.:.||.|.:||..::.:.|..:|..|:::::  .....|
Mouse    44 GLTPVARRHYSEAAA----------DREDDPNFFKMVEGFFDRGASIVEDKLVEDLK--TRESEE 96

  Fly    76 ERQARVTAILNLLGSVSTSVEVNFPIVRKNGTYEIISGYRSHHVRHRLPLKGGIRYALDVNESEV 140
            :::.||..||.::...:..:.::|||.|.:|::|:|.|||:.|.:||.|.||||||:.||:..||
Mouse    97 QKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEV 161

  Fly   141 KALAAIMTFKCACVNVPYGGSKGGICIDPKKYTVDELQTITRRYTMELLKRNMIGPGIDVPAPDV 205
            ||||::||:|||.|:||:||:|.|:.|:||.||.:||:.||||:||||.|:..|||||||||||:
Mouse   162 KALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDM 226

  Fly   206 NTGPREMSWIVDQYQKTFGYKDINSSAIVTGKPVHNGGINGRHSATGRGVWKAGDLFLKDKEWMD 270
            :||.||||||.|.|..|.|:.|||:.|.|||||:..|||:||.|||||||:...:.|:.:..:|.
Mouse   227 STGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMS 291

  Fly   271 LLKWKTGWKDKTVIVQGFGNVGSFAAKYVHEAGAKVIGIKEFDVSLVNKDGIDINDLFEYTEEKK 335
            :|....|:.|||.:||||||||..:.:|:|..|||.:|:.|.|.|:.|.||||..:|.::..:..
Mouse   292 ILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHG 356

  Fly   336 TIKGYPKAQESKEDLLVAETDILMPCATQKVITTDNAKDIKAKLILEGANGPTTPSGEKILLDKG 400
            :|.|:|||:..:..:|.|:.|||:|.|::|.:|..||..:|||:|.|||||||||..:||.|::.
Mouse   357 SILGFPKAKVYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERN 421

  Fly   401 VLLVPDLYCNAGGVTVSYFEYLKNINHVSYGKMNSKSTSELIIELMNSINESL------HECPDS 459
            ::::||||.|||||||||||:|||:||||||::..|...:....|:.|:.|||      |   ..
Mouse   422 IMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKH---GG 483

  Fly   460 QLPNICPNKKLKRIQQCTTEADIVDSALQTVMESAARGIKEMAHKFELCNDLRRAAYVWSSFKIF 524
            .:| :.|..:.:......:|.|||.|.|...||.:||.|...|.|:.|..|||.||||.:..|:|
Mouse   484 TIP-VVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVF 547

  Fly   525 QAMESSGIS 533
            :....:|::
Mouse   548 KVYNEAGVT 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bb8	NP_651140.1	GdhA	72..532	CDD:223411	223/465 (48%)
		ELFV_dehydrog_N	95..221	CDD:280903	77/125 (62%)
		NAD_bind_1_Glu_DH	242..517	CDD:133445	126/280 (45%)
Glud1	NP_032159.1	GdhA	104..546	CDD:223411	218/445 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843209
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.917438	Normalized mean entropy	S1271
OMA	1	1.010	-	-		QHG54967
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001473
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100455
Panther	1	1.100	-	-	O	PTHR11606
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R306
SonicParanoid	1	1.000	-	-		X1737
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.690