DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and bmp1b

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_005155463.1	Gene:	bmp1b / 559877	ZFINID:	ZDB-GENE-060818-2	Length:	970	Species:	Danio rerio

Alignment Length:	280	Identity:	85/280 - (30%)
Similarity:	122/280 - (43%)	Gaps:	59/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 KPDEELTANRVGNFSADADEMNPEELGSYLEGDMLVPQTDLIMKNGLPTQSSR-WPNGVVPYEIR 127
            |||   :.||     :.|:....:|       .:|..|:.|..:.....:..| ||||::||.|.
Zfish    74 KPD---SVNR-----SSANRNAKDE-------PVLANQSILRRRRAATARPERVWPNGIIPYIIS 123

  Fly   128 GNFNARDMATIENAIGEYHRRTCIRFVKRSSERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGC 192
            |||.....|..:.|:..:.:.||:.||:||.|..||.......||.|.|||.||..:.......|
Zfish   124 GNFTGSQRAIFKQAMRHWEKHTCVTFVERSVEESYIVFTLRPCGCCSFVGRRGGGPQAISIGKNC 188

  Fly   193 LSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKAA--RTEAFGVPYDYGSV 255
             .:.|..:|||.|.:||.||..|.:||.:|.|...|:|.....||.|..  ..::.|..||:.|:
Zfish   189 -DKFGIVVHELGHVIGFWHEHTRPDRDEHVDIFRENIQPGQEYNFIKMEPDDVDSLGEVYDFDSI 252

  Fly   256 MHYSKNAFS-------------ING-QPTILAMQANGADKMGQRNGFSDYDIQKLNRMYDC---- 302
            |||::|.||             ::| :|.|           |||...|..||.:..::|.|
Zfish   253 MHYARNTFSRGIYLDTMLPKYDVDGVRPPI-----------GQRTRLSKGDIAQARKLYRCPRCG 306

  Fly   303 -------GTVNAVPVAPGLP 315
                   |..:    :||.|
Zfish   307 ESLQDSAGNFS----SPGFP 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	71/215 (33%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	66/196 (34%)
bmp1b	XP_005155463.1	ZnMc_BMP1_TLD	109..303	CDD:239808	70/205 (34%)
		Astacin	111..303	CDD:279708	70/203 (34%)
		CUB	305..414	CDD:278839	4/22 (18%)
		CUB	418..527	CDD:278839
		EGF_CA	530..570	CDD:214542
		CUB	575..684	CDD:278839
		FXa_inhibition	691..726	CDD:291342
		CUB	731..840	CDD:278839
		CUB	844..957	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810