DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and tll2l

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001016661.1	Gene:	tll2l / 549415	XenbaseID:	XB-GENE-478930	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	242	Identity:	87/242 - (35%)
Similarity:	135/242 - (55%)	Gaps:	19/242 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 EG-DMLVPQTDL---IMKNGLPTQSSRW---PNG--VVPYEIRGNFNARDMATIENAIGEYHRRT 149
            || |.|:.|.|:   ::::.|...:.:|   .||  .||:.:...:....:|.|..|:.|:...|
Frog    54 EGIDQLLLQGDIAIRVVRSSLQCDNCKWDISSNGKVPVPFTVSPGYTKSQLALITAAMQEFETLT 118

  Fly   150 CIRFVKRSSERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQN 214
            |:.||.:::|::.|:|...| ||||.:||.||.|:|:|....|:.: |...|||.|.|||:||..
Frog   119 CVDFVPKTNEKNVININNGN-GCWSYIGRSGGVQQVSLSKQSCMVK-GIIQHELNHVLGFVHEHV 181

  Fly   215 RMERDGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFSINGQPTILAMQANGA 279
            |.:||.||.:...|:...::.||:.|. |...|:||||.|||||.:|||||:.....|..:.:..
Frog   182 RSDRDQYVNVVKKNILPDSLGNFDIAV-TNNLGLPYDYYSVMHYPRNAFSISPFLPTLITKPDPT 245

  Fly   280 DKMGQRNGFSDYDIQKLNRMYDC-------GTVNAVPVAPGLPAPAP 319
            .::|||.|.::.||.|:|::|:|       ..||....:|..|:..|
Frog   246 IQIGQRYGLTNLDIAKINKLYNCDVCSTLLSDVNGTLFSPSYPSAYP 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	75/199 (38%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	72/182 (40%)
tll2l	NP_001016661.1	ZnMc_hatching_enzyme	86..268	CDD:239810	73/184 (40%)
		CUB	272..382	CDD:238001	5/21 (24%)
		CUB	385..495	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.070