DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and mep1a

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001015767.1	Gene:	mep1a / 548484	XenbaseID:	XB-GENE-921661	Length:	704	Species:	Xenopus tropicalis

Alignment Length:	233	Identity:	80/233 - (34%)
Similarity:	113/233 - (48%)	Gaps:	14/233 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 GNFSADADEMNPEELGSYLEGDMLVPQTDLIMKNGLPTQSSRWPNGVVPYEIRGNFNARDMATIE 139
            |....|..::|.|...:..|||:::|..   .:|.|.....|| :..:||.:..|.:....:.|.
Frog    37 GELREDIPQINLESGLNLFEGDIVLPPR---ARNALLDDYYRW-SFPIPYILADNLDLNAKSVIL 97

  Fly   140 NAIGEYHRRTCIRFVKRSSERDYISIRGDNSGCWSSVG--RVGGKQEVNLQSPGCLSRPGTAMHE 202
            .|...:..::|:.|.....|..||..: ...||||.||  :||    .||.............||
Frog    98 KAFEMFRLKSCVDFKPYEGEPTYIHFQ-KFGGCWSMVGDLKVG----QNLSIGERCDYKAIVEHE 157

  Fly   203 LMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKAART--EAFGVPYDYGSVMHYSKNAFSI 265
            ::|||||.|||:|.:||.||.|.:..:.|...:||.|....  .....||||.|||||...:|:.
Frog   158 ILHALGFYHEQSRSDRDDYVKIWWEEITSGMEHNFNKYEDNYITDLNTPYDYESVMHYGPLSFNK 222

  Fly   266 NGQ-PTILAMQANGADKMGQRNGFSDYDIQKLNRMYDC 302
            |.. |||.|......|.:|||..||:.|:::|||||:|
Frog   223 NPDVPTITAKIEAFNDIIGQRLDFSEIDLERLNRMYNC 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	70/192 (36%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	65/185 (35%)
mep1a	NP_001015767.1	ZnMc_meprin	31..260	CDD:239809	79/231 (34%)
		MAM	270..431	CDD:366209
		MATH_Meprin_Alpha	430..596	CDD:239752
		EGF	635..>658	CDD:333761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100