DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-30

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_490795.5	Gene:	nas-30 / 190803	WormBaseID:	WBGene00003548	Length:	741	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	105/310 - (33%)
Similarity:	150/310 - (48%)	Gaps:	60/310 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GTALFGKPDEELTANRVGNFSADADEMNPEELGS-------YLEGDML--VPQTDLIMKNGLPTQ 113
            ||||...|  .|.|:|.|.           |||:       ..|.||:  |.|...|:   |..|
Worm   264 GTALGDAP--MLQAHRDGT-----------ELGANRALTNKLFESDMVLTVKQMKAIV---LAAQ 312

  Fly   114 SSRWPNG----------------VVPYEIRGNFNARDMATIENAIGEYHRRTCIRFVKRSSERDY 162
            .:|.|:|                |:|:..:|. :|:....|...:|.:.:.||:|:.:....:||
Worm   313 EARNPHGRKKRKVITGSVYRWKSVIPFRFKGG-DAKWKKLIREGLGLWEKETCVRWSENGPGKDY 376

  Fly   163 -ISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQY 226
             |..||  |||:|||||.||.|.::: ..||..: |...||:.|:|||.|||:|.:||.|:.::.
Worm   377 VIFFRG--SGCYSSVGRTGGSQLISI-GYGCEDK-GIVAHEVGHSLGFWHEQSRPDRDDYIHLRK 437

  Fly   227 NNVQSSAMNNFEKAA--RTEAFGVPYDYGSVMHYSKNAFSIN-GQPTILAMQANGADKMGQRNGF 288
            :.:......||||.:  ..|..|||||.||||||..|||:.: .|.||....:.....:|||...
Worm   438 DWIIKGTDGNFEKRSWEEIEDMGVPYDVGSVMHYGSNAFTKDWDQITIETKDSRYQGTIGQRQKL 502

  Fly   289 SDYDIQKLNRMYDCGTVNAVPVA-PGLPAPAPAPG------APAGSGNPI 331
            |..|::::||:| |.:|  .||| |.:....|.|.      .|.|.|..:
Worm   503 SFIDVKQVNRLY-CNSV--CPVALPCMHGGYPDPNNCAVCKCPDGLGGKL 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	75/207 (36%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	71/200 (36%)
nas-30	NP_490795.5	ZnMc_astacin_like	336..514	CDD:239807	70/182 (38%)
nas-30	NP_490795.5	CUB	564..648	CDD:412131
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920