DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-33

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_509086.2	Gene:	nas-33 / 186987	WormBaseID:	WBGene00003551	Length:	644	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	90/291 - (30%)
Similarity:	130/291 - (44%)	Gaps:	45/291 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 IIDLTPLGTALFGKPDEELTA---------NRVGNFSADADEMNPEELGSY-------------- 92
            :::.....||.|.:|.|....         ||......|.:.:.|.. |.|
Worm   106 VVNSVNQNTAAFQRPGESYDKVIQIMSSYFNRKSGSQYDINTVIPSS-GIYNNEMAANSKIAAVM 169

  Fly    93 LEGDM--LVPQTDLIMKNGLPTQSSRWPNGV-----VPY---EIRGNFNARDMATIENAIGEYHR 147
            .|.||  .|.|.:.:.:||...:.....||.     :||   :..||:.::    |.|.:..|.|
Worm   170 FESDMALTVSQMNKVAQNGFRVKRKMNLNGTTWSRNIPYRFLDTDGNWQSQ----ITNGLRHYER 230

  Fly   148 RTCIRFVKRSSERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHE 212
            .|||||.......||: :.....||:|||||:||.||::: ..|| ...|...||:.|||||.||
Worm   231 NTCIRFSLNGGGSDYL-VFSKGEGCYSSVGRLGGPQEISI-GDGC-ETLGIITHEVGHALGFWHE 292

  Fly   213 QNRMERDGYVAIQYNNVQSSAMNNFEKAARTEA--FGVPYDYGSVMHYSKNAFSING-QPTILAM 274
            |.|.|||.||.|...|..:.....|:|.:.:|.  :.:||||||||||...:||.:. ..|:..:
Worm   293 QARPERDSYVRINRQNAINGLEGQFDKRSWSEVNEYSLPYDYGSVMHYGPKSFSKSSTMNTVEPV 357

  Fly   275 QANGADKMGQRNGFSDYDIQKLNRMYDCGTV 305
            .....:.:|.|...|..|::.||..: |..:
Worm   358 DPAFINTIGNRVEPSFLDLKLLNTAF-CSNI 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	72/198 (36%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	71/191 (37%)
nas-33	NP_509086.2	Astacin	200..386	CDD:279708	70/193 (36%)
		ZnMc_astacin_like	203..381	CDD:239807	68/184 (37%)
		CUB	442..527	CDD:294042
		TSP1	553..595	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920