DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-1

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_499768.2	Gene:	nas-1 / 185811	WormBaseID:	WBGene00003520	Length:	270	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	82/212 - (38%)
Similarity:	122/212 - (57%)	Gaps:	8/212 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 DMLVPQTDLIMKNG--LPTQSSRWPNGVVPYEIRGNFNARDMATIENAIGEYHRRTCIRFVKRS- 157
            ||.:|........|  :..:..:||||.|||.:...:.:...|.:..|...|.:|||||||.:|
Worm    57 DMRIPFQRFKRGGGVAVAAEKDKWPNGRVPYILSAAYTSAQRAVLARAFDTYAKRTCIRFVPKSP 121

  Fly   158 SERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYV 222
            :::|||.|: ...||::...||||:|:|:| :..|:.. .|.:|||||.:||:||..|.:||.||
Worm   122 ADKDYIVIQ-KLDGCYADFSRVGGRQQVSL-ADECIDY-ATIIHELMHVIGFIHEHQREDRDSYV 183

  Fly   223 AIQYNNVQSSAMNNFEKAAR--TEAFGVPYDYGSVMHYSKNAFSINGQPTILAMQANGADKMGQR 285
            :|.|.||...|..:|:|.:.  ...:|..|||.|:|||..|..|.||:.||.|..::....||:.
Worm   184 SILYQNVIQGANTDFDKLSNLGLSYYGEHYDYSSIMHYEANEGSRNGKNTIEAKNSHFTAIMGKA 248

  Fly   286 NGFSDYDIQKLNRMYDC 302
            :.||..|::::||.|.|
Worm   249 SDFSTSDLRRVNRAYKC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	78/190 (41%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	74/183 (40%)
nas-1	NP_499768.2	Astacin	79..266	CDD:279708	78/190 (41%)
nas-1	NP_499768.2	ZnMc_astacin_like	82..263	CDD:239807	74/183 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920