DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-28

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_498342.3	Gene:	nas-28 / 185658	WormBaseID:	WBGene00003546	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	327	Identity:	92/327 - (28%)
Similarity:	154/327 - (47%)	Gaps:	46/327 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FLVLALALSSCQALPYVSYDDVDDTEVIELPGNGI------EEIPPTLGKDIIDLTPLGTALFGK 64
            |:...|...:.:||..:..|:..|:........||      ..:|...|:.       |.|
Worm     8 FIPFVLGAPTQKALEKILVDNNPDSVTNREKIRGIIDKAFENRVPRVQGRQ-------GVA---- 61

  Fly    65 PDEELTANRVG---NFSADADEMNPEELGSY-LEGDMLVPQTD-----LIMKNG--------LPT 112
            |.....|...|   |.:...:|:| :::..| .|.|:::.:..     ..::||        :..
Worm    62 PPVTFAALNYGPKNNQTKKFEELN-QDINEYTFESDIMLNEKQAKHIATAIENGNYRSKRQAIVD 125

  Fly   113 QSSRWPNGV-VPYEIRGNFNARDMATIENAIGEYHRRTCIRFVK--RSSERDYISIRGDNSGCWS 174
            .::.|...| :.|:.....:|.::|.:..||..::..:|:.|.:  .:..|.::|..|   ||||
Worm   126 TTNFWSVSVPIFYQFDTKLSATNIANVRKAIQFWNDNSCLSFKEDNNAKNRLFLSSAG---GCWS 187

  Fly   175 SVGR-VGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFE 238
            .||: |....::....|.| ...|||.||||||:||.|:|:|.:||.||.:.::|:..|...||:
Worm   188 YVGKQVDMPYQMVSVGPNC-DTFGTATHELMHAIGFWHQQSRADRDNYVYVDFSNIIPSQAYNFQ 251

  Fly   239 KAA--RTEAFGVPYDYGSVMHYSKNAFSINGQP-TILAMQANGADKMGQRNGFSDYDIQKLNRMY 300
            |.|  :.:...:||||||||.|...||:::... ||||.:....:.||||...:..||..:|::|
Worm   252 KMAVDQAQLLNLPYDYGSVMQYYPYAFAVDSSKYTILAKENGFQNSMGQREAPAFSDIIGVNKLY 316

  Fly   301 DC 302
            :|
Worm   317 NC 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	69/194 (36%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	66/187 (35%)
nas-28	NP_498342.3	Astacin	135..320	CDD:279708	67/188 (36%)
		ZnMc_astacin_like	135..316	CDD:239807	65/184 (35%)
		CUB	393..480	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920