DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-12

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_501871.2	Gene:	nas-12 / 182848	WormBaseID:	WBGene00003531	Length:	384	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	73/228 - (32%)
Similarity:	115/228 - (50%)	Gaps:	23/228 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 GDMLVPQTDLIMK----------NGLPTQSS---RWPNGVVPYEIRGNFNARDMATIENAIGEYH 146
            ||||:....||..          .|:..:.|   ||.|.:|||.|...::......:.:::..:.
Worm    48 GDMLLTPAQLIRYENSKDSDLSIRGVSIKGSSMNRWSNNIVPYVISPQYSPAQKQILVSSLRYFE 112

  Fly   147 RRTCIRFVKRSSERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLH 211
            |.:|.:||:|:::.||:.| ....||:|.||::||:|.::| :..|:: .....||:|||:||.|
Worm   113 RVSCFKFVERTTQNDYLFI-VPLDGCYSYVGKIGGRQTLSL-AADCIA-DYIIWHEMMHAIGFEH 174

  Fly   212 EQNRMERDGYVAIQYNNVQSSAMNNFEKAARTEAFGVP--YDYGSVMHYSKNAFSINGQPTILAM 274
            |..|.:||.::.:.|.||....|.||:| .:|.....|  ||:.|:|||...||........:.:
Worm   175 EHQRPDRDSFIRVDYANVIPGQMINFDK-LKTSHVEYPDIYDFKSIMHYDGYAFGRVDTARRVRL 238

  Fly   275 QANGADKMG----QRNGFSDYDIQKLNRMYDCG 303
            ......|.|    ....|:..||:||||:..||
Worm   239 ATMTPLKPGVTLEDNMKFTATDIEKLNRLGQCG 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	65/194 (34%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	61/186 (33%)
nas-12	NP_501871.2	Astacin	81..272	CDD:279708	65/195 (33%)
		ZnMc_astacin_like	85..267	CDD:239807	60/185 (32%)
		ShK	286..325	CDD:279838
		ShK	347..384	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5777
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.870