DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-7

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_495552.2	Gene:	nas-7 / 182368	WormBaseID:	WBGene00003526	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	93/249 - (37%)
Similarity:	141/249 - (56%)	Gaps:	25/249 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 ADEMNPEEL-GSYL--------EGDMLVPQTDLIMKNGLPTQSSRWPNGVVPYEIRGNFNARDMA 136
            ||::..||| |.::        :.|:.:|:..  .:||:...:..|||..:||.|..:::..:.|
Worm    46 ADKLTREELFGKHIPVEVVNDFKSDIRLPRRH--KRNGVSRAAKLWPNARIPYAISPHYSPHERA 108

  Fly   137 TIENAIGEYHRRTCIRFVKR-SSERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAM 200
            .:..|:.:||.:||||||.| :.|.||:.| |...||:|.|||..|.|.::|.: ||:.. .|.:
Worm   109 LLAKAVKQYHEKTCIRFVPRQTGEPDYLFI-GKVDGCFSEVGRTSGVQVLSLDN-GCMEY-ATII 170

  Fly   201 HELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKA--ARTEAFGVPYDYGSVMHYSKNAF 263
            ||:||.:||.||..|.:||.::.|.:.|:...|::.|.|.  ::|..:|.||||.|::||...||
Worm   171 HEMMHVVGFYHEHERWDRDNFIDIIWQNIDRGALDQFGKVDLSKTSYYGQPYDYKSILHYDSLAF 235

  Fly   264 SINGQPTILAMQANGADKMGQRNGFSDYDIQKLNRMYDCGTVNAVPVAPGLPAP 317
            |.||.||:|....:..  :|....|||.||.|:||||:|      ||...:.||
Worm   236 SKNGFPTMLPKVKSAT--IGNARDFSDVDISKINRMYNC------PVEKSVTAP 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	79/190 (42%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	74/183 (40%)
nas-7	NP_495552.2	Astacin	87..274	CDD:279708	79/197 (40%)
		ZnMc_astacin_like	91..270	CDD:239807	74/183 (40%)
		ShK	347..382	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I2268
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		mtm4854
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.920