DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-4

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001254938.1	Gene:	nas-4 / 182259	WormBaseID:	WBGene00003523	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	322	Identity:	109/322 - (33%)
Similarity:	163/322 - (50%)	Gaps:	59/322 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVLALALSSCQALPYVSYDDVDDTEVIELPGNGIEEIPPTLGKDIIDLTPLGTALFGKPDEELTA 71
            ||.....::|.....|:...|.||.|                                |..|.|.
Worm     9 LVFCAIFATCWTASVVNNKQVIDTSV--------------------------------PQTETTL 41

  Fly    72 NRVGNFSADADE-----------MNPEELGSYLEGDML-------VPQTDLIMKNGLPTQSSRWP 118
            |. .:|.:|..:           .:...:|:|.|||:|       |.:.:.:.:|.:.....|||
Worm    42 ND-ADFHSDLHQRYDLQTLGIKVKDDPTIGNYSEGDILLESPKKFVEENNKLGRNAIKQIYRRWP 105

  Fly   119 NGVVPYEIRGNFNARDMATIENAIGEYHRRTCIRFVKR--SSERDYISIRGDNSGCWSSVGRVGG 181
            |..:||.:...:.:...:.|.||:.|||.:||::||.|  |...||:.|..| .||:|.||:.||
Worm   106 NNEIPYTLSSQYGSYARSVIANAMNEYHTKTCVKFVARDPSKHHDYLWIHPD-EGCYSLVGKTGG 169

  Fly   182 KQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKAART--E 244
            ||.|:|.| ||: :.||.:||||||:||.|||:|.:||.|:.:.:.||.:.|.:.|||....  .
Worm   170 KQPVSLDS-GCI-QVGTIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVIS 232

  Fly   245 AFGVPYDYGSVMHYSKNAFSINGQPTILAMQANGADKMGQRNGFSDYDIQKLNRMYDCGTVN 306
            ....||||.|:|||...|||.:|:.| |..:.:|:::||||..|||.|::|:|::|:|..|:
Worm   233 HLDEPYDYASIMHYGPYAFSGSGKKT-LVPKKSGSERMGQRVKFSDIDVRKINKLYNCPGVS 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	86/191 (45%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	81/184 (44%)
nas-4	NP_001254938.1	Astacin	102..290	CDD:279708	85/191 (45%)
nas-4	NP_001254938.1	ZnMc_astacin_like	106..287	CDD:239807	81/184 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I2268
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I2674
Isobase	1	0.950	-	0	Normalized mean entropy	S5777
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		mtm4854
orthoMCL	1	0.900	-	-		OOG6_101406
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.820