DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-37

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001024413.1	Gene:	nas-37 / 181208	WormBaseID:	WBGene00003553	Length:	765	Species:	Caenorhabditis elegans

Alignment Length:	338	Identity:	104/338 - (30%)
Similarity:	151/338 - (44%)	Gaps:	69/338 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LKVFLVLALALSSCQALPYVSYDDVDD-TEVIEL-----------------PGNGIEEIPPTLGK 49
            |||.|.| :.|.|..:..|::.|.|.| .||.||                 |. .|:.|...:.|
Worm     7 LKVCLAL-IGLVSIVSTAYIANDVVSDYAEVKELLAAFYRKHAKKYGHDYDPA-AIQAIAENMDK 69

  Fly    50 DIIDLTPLGTALFGKPDE-ELTANRVGNFSADADEMNPEELGSYLEGDML--VPQTDLIMKNGLP 111
            .:            |.|: |.|.||             :......|.|::  :||.:.::.....
Worm    70 SV------------KNDKTEATVNR-------------KLWNEVFENDIILTLPQAESLLSESNS 109

  Fly   112 TQSSR---------WPNGVVPYEIRGNFNA-RDMATIENAIGEYHRRTCIRFVKRSSERDYIS-I 165
            .:|.|         |||..:.||..|.... |.:  |.:||....:..|.:|.:...:||.:. .
Worm   110 PRSRRQAHPDPRNFWPNLTISYEFYGGEETWRQL--IRSAIRHVEQNVCFKFKENGGDRDGLRYY 172

  Fly   166 RGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQ 230
            ||  :||||:||||||:|.|:: ..||.|. |...||.:||||..|||:|.:||.:::|..:.:.
Worm   173 RG--NGCWSNVGRVGGRQLVSI-GYGCDSL-GIVSHETLHALGLWHEQSRDDRDNFISIVADKIT 233

  Fly   231 SSAMNNFEK--AARTEAFGVPYDYGSVMHYSKNAFSIN-GQPTILAMQANGADKMGQRNGFSDYD 292
            .....||.|  ||.::..|.|||.||||||...:|:.: ...||........:.:|||:|.|..|
Worm   234 RGTEGNFAKRTAANSDNLGQPYDLGSVMHYGAKSFAYDWSSDTIKTRDWRYQNTIGQRDGLSFKD 298

  Fly   293 IQKLNRMYDCGTV 305
            .:.:|..| |..|
Worm   299 AKMINTRY-CSNV 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	73/201 (36%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	68/185 (37%)
nas-37	NP_001024413.1	Astacin	122..309	CDD:279708	72/193 (37%)
		ZnMc_astacin_like	126..306	CDD:239807	68/185 (37%)
		CUB	370..455	CDD:214483
		TSP1	579..626	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020