DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-38

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001359993.1	Gene:	nas-38 / 180407	WormBaseID:	WBGene00003554	Length:	727	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	76/244 - (31%)
Similarity:	115/244 - (47%)	Gaps:	19/244 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 NFSADADEMNPEELGSYLEGDMLVPQTDLIMKNGLPTQSSR-------------W-PNGVVPYEI 126
            |.....||:.......|.:||:.:.:..:.:.....||..|             | ..|.:.::.
Worm    70 NTGVHHDELAVNNADEYFQGDVDLSEQQVKIIEDQFTQGKREKRKIGRNPLYKKWDTRGPISFDY 134

  Fly   127 RGNFNARDMATIENAIGEYHRRTCIRFVKRSSERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPG 191
            ..:...:....|.:|:..:.:.||:||.:.....|.:.. .|..||.|.||||||.|.:::.:||
Worm   135 AESIPFQTRQKIRSAMLLWQQHTCLRFEEGGPNVDRLEF-FDGGGCSSFVGRVGGTQGISISTPG 198

  Fly   192 CLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKAA--RTEAFGVPYDYGS 254
            | ...|...||:.||||..|||.|.:::.::||.|||:..|..|||:...  ..|.:.:|||.||
Worm   199 C-DVVGIISHEIGHALGIFHEQARPDQERHIAINYNNIPLSRWNNFQAVGENHAETYNLPYDTGS 262

  Fly   255 VMHYSKNAFSING-QPTILAMQANGADKMGQRNGFSDYDIQKLNRMYDC 302
            ||||....|:.:. .|||..::......:|||.|.|..|.|.:|..|.|
Worm   263 VMHYGPYGFASDPYTPTIRTLERVQQSTIGQRAGPSFLDYQAINMAYGC 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	68/204 (33%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	64/183 (35%)
nas-38	NP_001359993.1	Astacin	122..313	CDD:366617	67/192 (35%)
		CUB	367..466	CDD:214483
		TSP1	613..658	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920