DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and nas-32

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_503351.3	Gene:	nas-32 / 178595	WormBaseID:	WBGene00003550	Length:	653	Species:	Caenorhabditis elegans

Alignment Length:	309	Identity:	85/309 - (27%)
Similarity:	122/309 - (39%)	Gaps:	51/309 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 IEEIPPTLGK-DIIDLTPLGTALFGKPDEELTANRVGNFSADADEMNPEELGSYLEGDMLVPQTD 103
            |.|.||.|.. ::.:...|...|| :.|..|..|::...|::....:..:
Worm   153 ITENPPALDMFEVNERAGLNEYLF-QGDINLNNNQIAKISSEQSSKSRRK--------------- 201

  Fly   104 LIMKNGLPTQSSRWPNGVVPYEIRGNFNARDMATIENAIGEYHRRTCIRFVKRSSERDYISIRGD 168
               |..:...:..||..||.|.............:.:||......||::|...|:..:.:.| ..
Worm   202 ---KRQIDNLAQFWPGKVVYYYFDSGLTTTVQQIVRDAITFLESNTCLKFELNSTATNRVKI-FS 262

  Fly   169 NSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSA 233
            ..||:|..|.:||:|.::| ..|| ...|||.||:.|.||..|.|.|.:||.||.|...:|..|:
Worm   263 GVGCYSDTGMLGGEQTLSL-GYGC-EVTGTAAHEIAHTLGLFHTQMRSDRDDYVTIDLTDVPESS 325

  Fly   234 MNNFEKAARTEAFG---VPYDYGSVMHYSKNAFSINGQPTILAMQANGADKMGQRNGFSDY---- 291
            ..||.|.  |||..   |.|:|||.||||..||..:|          |.|.:..::....|
Worm   326 QQNFIKL--TEATSTNLVDYEYGSFMHYSGRAFVSSG----------GVDSIVPKDPVMVYTMGG 378

  Fly   292 ------DIQKLNRMYDCGTVNAVPVAPG---LPAPAPAPGAPAGSGNPI 331
                  |::.||..|.|.....:....|   .||.......|.|.|..:
Worm   379 RIVTFLDLKMLNTHYSCSCPTILSCGNGGFTNPANCSVCICPYGFGGAL 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	66/200 (33%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	62/193 (32%)
nas-32	NP_503351.3	Astacin	210..397	CDD:279708	66/201 (33%)
		ZnMc_astacin_like	214..393	CDD:239807	62/193 (32%)
		CUB	464..>528	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920