DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and astl2d.2

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_031756346.1	Gene:	astl2d.2 / 105947175	XenbaseID:	XB-GENE-22069740	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	85/216 - (39%)
Similarity:	123/216 - (56%)	Gaps:	15/216 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 LEGDMLVPQTDLIMKNGLPTQSSRW--PNGV--VPYEIRGNFNARDMATIENAIGEYHRRTCIRF 153
            ::||:.|    .:.::.:......|  .||:  |||.:...:::..:.||.:|:..|...||::|
Frog    79 VQGDIAV----RVSRSTIVCTDCFWQKSNGIVYVPYTLDKQYSSDQINTITSAMEVYSTLTCVQF 139

  Fly   154 VKRSSERDYISI-RGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRME 217
            |..:.|.|||:| .||  ||||.:||.||.|.|:::...|.|. ||.||||.|||||:|||:|.:
Frog   140 VPYTDEEDYIAITSGD--GCWSYMGRQGGAQVVSVEKGYCTSE-GTTMHELNHALGFVHEQSRSD 201

  Fly   218 RDGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFS-INGQPTILAMQANGADK 281
            ||.||.|.|..:....:.||:| ..|......|||.|:|||...||| ..||.||:| :.|....
Frog   202 RDNYVDIMYQYISPGDIVNFKK-METNNLNTTYDYHSIMHYPAWAFSNTTGQNTIVA-KLNPNTP 264

  Fly   282 MGQRNGFSDYDIQKLNRMYDC 302
            :|..:..::.||.|:||:|.|
Frog   265 LGPGSTMTNLDITKINRLYQC 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	82/193 (42%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	79/184 (43%)
astl2d.2	XP_031756346.1	ZnMc	103..285	CDD:412141	80/186 (43%)
		CUB	288..399	CDD:238001
		CUB	402..513	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060