DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and astl2d.1

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_004913424.2	Gene:	astl2d.1 / 100495740	XenbaseID:	XB-GENE-22069737	Length:	604	Species:	Xenopus tropicalis

Alignment Length:	331	Identity:	106/331 - (32%)
Similarity:	162/331 - (48%)	Gaps:	50/331 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VSYDDVDDTEVIELPGNGIEEIPPTLGKD---IIDLTPLGTALFGKPDEE------LTANRVGNF 77
            |:.|..||..:| :..:.::.:.|..|.|   |::...:.|.   .||..      :.|::|...
Frog    84 VTPDSGDDFSMI-MNADKVQPVTPDSGDDFSMIMNADKVQTV---TPDSSDDFSTIMNADKVQTV 144

  Fly    78 SADADE-----MNPEELGSY--LEGDMLVPQTDLIMKNGLPTQSSRWP--NGV--VPYEIRGNFN 131
            :.|.::     ||.::....  :.||:.:.    :.::.|......|.  ||.  |||.:...::
Frog   145 TPDHNDVFSMIMNADKASRVRRVHGDIAIG----VSRSALNCTDCLWQKINGTVYVPYTLDEQYS 205

  Fly   132 ARDMATIENAIGEYHRRTCIRFVKRSSERDYISI-RGDNSGCWSSVGRVGGKQEVNLQSPGCLSR 195
            ..::.||..|:..|...||::||..:.|.|||:| .||  ||||.:||.||.|.|::|...|.|.
Frog   206 NNEVNTIMTAMQVYATLTCVQFVPYTDEDDYIAITSGD--GCWSYMGRQGGAQVVSVQKTYCTSE 268

  Fly   196 PGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSK 260
             ||.||||.|||||:||.:|.:||.||.|.|..:....:.|||| ..|......|||.|:|||:.
Frog   269 -GTTMHELNHALGFVHEHSRSDRDNYVDIMYQYISPGDVANFEK-MNTNNLNTAYDYHSIMHYAA 331

  Fly   261 NAFS-INGQPTILAMQANGADKMGQRNGFSDYDIQKLNRMYDC-----------GTVNAVPVAPG 313
            .:|| ..||.||:| :.:....:|..:..:..||.|:||:|.|           ||:.:.    .
Frog   332 YSFSNTTGQNTIVA-KPDPNTPLGPGSTMTSLDITKINRLYQCDVCSYFLTDATGTITSA----N 391

  Fly   314 LPAPAP 319
            .|:|.|
Frog   392 YPSPYP 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	81/204 (40%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	78/184 (42%)
astl2d.1	XP_004913424.2	ZnMc_hatching_enzyme	191..373	CDD:239810	79/186 (42%)
		CUB	376..485	CDD:395345	5/26 (19%)
		CUB	490..601	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050