DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and astl2d.5

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_031756347.1	Gene:	astl2d.5 / 100495579	XenbaseID:	XB-GENE-22069752	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	239	Identity:	88/239 - (36%)
Similarity:	126/239 - (52%)	Gaps:	23/239 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VP--QTDL---IMKNGLPTQSSRW--PNGV--VPYEIRGNFNARDMATIENAIGEYHRRTCIRFV 154
            ||  |.|:   :.::.:......|  .||.  |||.:...::..::.|:.:|:..|...||::||
Frog    56 VPRVQEDIAVGVSRSAITYTECLWQKTNGTVYVPYTLDDKYSNSEVNTMTSAMEVYATLTCVQFV 120

  Fly   155 KRSSERDYISI-RGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMER 218
            ..:.|.||::| .||  ||||.:||..|.|.|:::...|.|. ||.||||.|||||:|||:|.:|
Frog   121 PYTDEDDYVNITSGD--GCWSYMGRQRGAQVVSVEKGYCTSE-GTTMHELNHALGFVHEQSRSDR 182

  Fly   219 DGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFS-INGQPTILAMQANGADKM 282
            |.||.|.|..:....:..|:| ..:...|..|||.|||||...||| ..||.||:| :.|....:
Frog   183 DNYVNIMYQYISPGDVAEFKK-MESNNLGTTYDYRSVMHYPAWAFSNTTGQNTIVA-KPNPNIII 245

  Fly   283 GQRNGFSDYDIQKLNRMYDCGT-------VNAVPVAPGLPAPAP 319
            |..|..:..||.|:||:|:|..       .|....:...|:|.|
Frog   246 GAGNTMTSLDIIKINRLYECDVCSSLLTDANGTVTSANYPSPYP 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	80/193 (41%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	77/184 (42%)
astl2d.5	XP_031756347.1	ZnMc	83..265	CDD:412141	78/186 (42%)
		CUB	268..377	CDD:395345	4/22 (18%)
		CUB	382..493	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010