DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and astl2f

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_002934133.3	Gene:	astl2f / 100495416	XenbaseID:	XB-GENE-22069764	Length:	624	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	107/308 - (34%)
Similarity:	152/308 - (49%)	Gaps:	27/308 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NGIEEIPPTLGKDIID--LTPLGTALFGKPDEELTANRVGNFSADADEMNPEELGSYLEG--DML 98
            :|:..:|.|:...:|:  |..:...|.....:|  ..:..|.||..|     .|...||.  |..
Frog   122 SGLVNVPYTMQYIVIETYLQEMKRTLMSLSLQE--GQKEDNSSASLD-----TLSQILEANKDTN 179

  Fly    99 VP--QTDLIMKNGLPT---QSSRWPNGV-----VPYEIRGNFNARDMATIENAIGEYHRRTCIRF 153
            ||  |.|::.|.|..|   .|..||...     |||.|...|:..:...|:.|:.|....:||||
Frog   180 VPLVQGDILEKLGRSTTNCTSCLWPRATSGLVNVPYTIASVFDDSEQELIQGALNELMTLSCIRF 244

  Fly   154 VKRSSERDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMER 218
            ..|:.|.|::|.:..| |||||||:.||.|||::...||:|. |...||.:|||||:||..|.:|
Frog   245 KARTIETDFLSFQSGN-GCWSSVGKTGGSQEVSVSKSGCMSH-GIIQHETLHALGFIHEHCRSDR 307

  Fly   219 DGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAF-SINGQPTILAMQANGADKM 282
            |.||.|.|..:.....::|.| ..:...|:.|||.|||||.:..| :..||.||:. :.:.:..:
Frog   308 DNYVDIIYKYISEGDRSSFTK-VNSNNLGLQYDYSSVMHYGRFTFTNTPGQATIIP-KPDLSVPI 370

  Fly   283 GQRNGFSDYDIQKLNRMYDCGTV-NAVPVAPGLPAPAPAPGAPAGSGN 329
            |||.|.|..|:.|||::|:|... |.:....|....|..|.|...:.|
Frog   371 GQRYGVSSLDVAKLNKLYNCNICSNLLSDTSGTFTSANYPSAYPPNSN 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	78/193 (40%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	74/186 (40%)
astl2f	XP_002934133.3	ZnMc	209..390	CDD:412141	75/184 (41%)
		CUB	394..504	CDD:238001	6/25 (24%)
		CUB	507..621	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	LDO	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.150