DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and astl2g

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_002934115.1	Gene:	astl2g / 100491886	XenbaseID:	XB-GENE-22069768	Length:	505	Species:	Xenopus tropicalis

Alignment Length:	281	Identity:	102/281 - (36%)
Similarity:	154/281 - (54%)	Gaps:	28/281 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 DIID----LTPLGTALFGKPDEELTANRVGNFSADADEMNPEE------LGSYLEG-DMLVPQTD 103
            ||:.    :..|...:.|.| .|:........:...:|..||.      :....:| ..|:.::|
Frog     2 DIVTSCLIVASLMQCILGAP-LEIYFEEANKIAVSQEEAKPEPKDVFTIISETNKGVKKLLHESD 65

  Fly   104 LIM---KNGLPT--QSSRW--PNGV--VPYEIRGNFNARDMATIENAIGEYHRRTCIRFVKRSSE 159
            :::   :|.:..  .:.||  .:|:  |||.|..||:|.:::.|.:|:.::...||:.||.|:.|
Frog    66 IVVSVDRNAMKCDGDTCRWKTSDGIVRVPYTISANFSATEVSVIVDAMQDFATLTCVNFVPRTVE 130

  Fly   160 RDYISIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAI 224
            .||:.|..| |||||.||:.||.|||:|...||:.: ||..|||.|||||.|||:|.:||.||.|
Frog   131 PDYLQIIPD-SGCWSYVGKTGGAQEVSLNQGGCVGK-GTVQHELNHALGFYHEQSRSDRDNYVNI 193

  Fly   225 QYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFSINGQPTI--LAMQANGADKMGQRNG 287
            ...|:..:::.||:| ..|...|..|||.|||||.:|||:  .||.:  :..:.|....:|||.|
Frog   194 LTGNIIPASIGNFDK-YNTNNLGQEYDYSSVMHYGRNAFA--KQPGLDTIVPKPNPNVPIGQRYG 255

  Fly   288 FSDYDIQKLNRMYDCGTVNAV 308
            .|:.||.|:|::|.||..:.|
Frog   256 LSNLDISKINQLYQCGACSTV 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	87/193 (45%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	83/184 (45%)
astl2g	XP_002934115.1	Astacin	83..272	CDD:279708	87/193 (45%)
		ZnMc_hatching_enzyme	88..270	CDD:239810	84/186 (45%)
		CUB	270..384	CDD:238001	3/7 (43%)
		CUB	387..497	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.070