DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6763 and astl3a.1

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_002944440.3	Gene:	astl3a.1 / 100491875	XenbaseID:	XB-GENE-22069668	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	104/293 - (35%)
Similarity:	147/293 - (50%)	Gaps:	41/293 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LFGKPDEELTANRVGNFSADADEM---NPEELGS--------------YLEGDMLVP--QTDLIM 106
            :|...||.|..|   |..|:.|.:   ..|:.|:              ....|:.:|  :.|:|.
Frog    24 VFYSEDERLAEN---NAVANKDTLKAQGKEDTGTAKTQDSMDIHSMILAANKDIRLPTREGDIIQ 85

  Fly   107 ---KNGLPTQSSRWPNGV-----VPYEIRGNFNARDMATIENAIGEYHRRTCIRFVKRSSERDYI 163
               :|.:...|..||...     |||....::||..:|..:.|:.|:...||:||...::|.|::
Frog    86 NPGRNAINCTSCLWPKSADGTVPVPYNFSYSYNADQLALFKTAMQEFETLTCVRFRPWTTESDFL 150

  Fly   164 SIRGDNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNN 228
            :| ..|.||.||:|:.||.|.|.|.:.||:|. |...|||.|||||.|||||.:||.||.|...|
Frog   151 NI-VSNGGCASSIGKSGGAQRVALDANGCMSM-GIIEHELNHALGFYHEQNRSDRDDYVIIHPEN 213

  Fly   229 VQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFSINGQPTILAMQANGADKMGQRNGFSDYDI 293
            :...::|||.| ..|...|..|||.|||||:::|||.||:.|| ..:.|....:|||||.|..||
Frog   214 ILPDSLNNFNK-YDTNNLGTEYDYNSVMHYARDAFSKNGKATI-EPKPNPNVPIGQRNGLSVLDI 276

  Fly   294 QKLNRMYDCGTV-------NAVPVAPGLPAPAP 319
            .|:|::|.|...       |...::...|:..|
Frog   277 SKINKLYGCNVCSNLLSNPNGTMISANYPSAYP 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	85/192 (44%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	81/185 (44%)
astl3a.1	XP_002944440.3	ZnMc_hatching_enzyme	104..285	CDD:239810	82/184 (45%)
		CUB	289..397	CDD:238001	3/21 (14%)
		CUB	402..512	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060