DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6763 and mep1b

DIOPT Version :9

Sequence 1:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001096352.1	Gene:	mep1b / 100124942	XenbaseID:	XB-GENE-1001365	Length:	722	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	94/248 - (37%)
Similarity:	134/248 - (54%)	Gaps:	10/248 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LFGKPDEELTANRV-GNFSADADEMNPEELGSYLEGDMLVPQTDLIMKNGLPTQSSRWPNGVVPY 124
            :.|.|.::.|...| |....|..::|........|||:::..|:  .:|.:.....|||. .|||
Frog    16 VIGVPLQDNTEIDVDGGKKLDIFDINEGAGLDLFEGDIILADTN--QRNSIIGDRYRWPI-PVPY 77

  Fly   125 EIRGNFNARDMATIENAIGEYHRRTCIRFVKRSSERDYISIRGDNSGCWSSVGRV-GGKQEVNLQ 188
            .:..:......|.:..|...|..:|||.|.....|.:|||:..| |||:|.||.: .|||:::|
Frog    78 FLEDSLEINAKALVLEAFERYRLKTCIDFKPWEGEPNYISVFKD-SGCYSYVGNLRQGKQQLSL- 140

  Fly   189 SPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFE--KAARTEAFGVPYD 251
            ...| .|..|..||.:|||||.|||:|.:||.||.|.::.:.....:||.  ...|:.:..||||
Frog   141 GVNC-DRIATIQHEFLHALGFWHEQSRADRDDYVTIVWDRILPGREHNFNVYDDTRSNSLNVPYD 204

  Fly   252 YGSVMHYSKNAFSINGQPTILAMQANGADKMGQRNGFSDYDIQKLNRMYDCGT 304
            |.|||||||.||....:|||:......:|.:|||..|||||::||||:|:|.:
Frog   205 YTSVMHYSKTAFQNGSEPTIVTKIDAFSDVIGQRMDFSDYDLEKLNRLYNCSS 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	82/190 (43%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	77/183 (42%)
mep1b	NP_001096352.1	ZnMc	26..255	CDD:412141	90/234 (38%)
		MAM	265..428	CDD:395504
		MATH	427..590	CDD:351761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010