Protein Alignment orb and Cpeb2

DIOPT Version :10

• Sequence 1: NP_524460.2
• Gene: orb / 42752
• FlyBaseID: FBgn0004882
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: XP_038948724.1
• Gene: Cpeb2 / 360949
• RGDID: 1307485
• Length: 1039
• Species: Rattus norvegicus
• Alignment Length: 876
• Identity: 227/876 - (25%)
• Similarity: 333/876 - (38%)
• Gaps: 277/876 - (31%)

  Fly    90 LCGASTANEVVGTGQTPSTSAPILGAGGG---------GRANGVTAGAATATGVGVGAGGTLPGP 145
            :.|..:|.|....|..||| .|:..|.|.         ...:.:..|||    :|..|..:|..|
  Rat   278 VAGEGSAAEPPNAGLPPST-PPVNPAPGSMESPNHPLLNSPSTLLPGAA----LGTSAFSSLQSP 337

  Fly   146 GVPSIQGGGGGGVVGQQTNASCNTSAANPSASFGGNGSSSDVNNLLLASAAAAAAAAAGDGAQLS 210
            .:|...||||||                |....||.||             |:.....|.|...|
  Rat   338 DLPHPGGGGGGG----------------PPGGGGGGGS-------------ASPPPLPGFGTPWS 373

  Fly   211 ANAAAYAPLTPSSTHSSASPGTKSNFDYFQFENVAQSNPLKAFQRTNISFDCSAPLSPSTPTSIY 275
            ...|:..|..|..                    ..|..|.:..|         .|..|..|
  Rat   374 VQTASPPPPQPPP--------------------APQQQPSQQQQ---------PPQQPPQP---- 405

  Fly   276 NRSFHSSPLVSDSSNSSSGIGL----------SMDSINMFYNQQQQQQQP---------EQQGYT 321
                  .|..|.::....|.|.          |.||.|.||........|         ...|..
  Rat   406 ------QPPGSSAATPGGGGGAGGSLSAMPPPSPDSENGFYPGLPSSMNPAFFPSFSPVSPHGCA 464

  Fly   322 SL-----GNSMGSGLGLSLANASTRSNSPESQNSSNSTTEQNLLDMINLLSVNSNKIPHQQQQQQ 381
            .|     |...|.|.|           .|.|..:..:....||                 .|||.
  Rat   465 GLSVPAGGGGGGGGFG-----------GPFSAPAVPAPPAMNL-----------------PQQQP 501

  Fly   382 QQQQQQQQQQQQNQQQLQVQQQHQ------LQQQFVNLNRNYEQQI----------SANLGS--- 427
            .....||.|.:::....|:|||||      |||:   .:.|:.|.:          |:..|:
  Rat   502 PPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQR---NSYNHHQPLLKQSPWSNHQSSGWGTASM 563

  Fly   428 ---QQHGFEH---NGVGVGASS----------SGN---------------------ENCFSQYNL 455
               ..||.:|   ..:|:..:.          |||                     :|.|...|.
  Rat   564 SWGAMHGRDHRRSGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNN 628

  Fly   456 EN---------------------------------ITSVDMELAKLQNLQRINTLK--LLH-AQA 484
            .|                                 .:.:|.:.:::.:...:::|:  |:. .:|
  Rat   629 SNTLLPLQVRMVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMRA 693

  Fly   485 QQMPLINQLLQSYAG--NAI---GSVGGSNLGNLMSAG----------GSSLMTEMAGNVGGIIT 534
            :..||..:|...:.|  |.:   |.|.|:   .|.|.|          |.|.:..:..::
  Rat   694 EHDPLKGRLSYPHPGTDNLLMLNGWVPGA---ELKSCGLHARSYGRRRGRSSLFPIDDSL----- 750

  Fly   535 TNDGHLDRVAKFYKSSAALCDATCTWSGHLPPRSHRMLNYSPKVFLGGIPWDISEQSLIQIFKPF 599
            .:|||.|:|       ..|...|| :|.|  ....|:..:|.|||:||:|.||.|..:...|:.|
  Rat   751 LDDGHSDQV-------GVLNSPTC-YSAH--QNGERIERFSRKVFVGGLPPDIDEDEITASFRRF 805

  Fly   600 GSIKVEWPGKEQQAA--QPKGYVYIIFESDKQVKALLSACVLQVDDSHCGRNYFFKISSRRIKSK 662
            |.:.|:||.|.:..:  .||||.:::|:.:..|:||:.||:     ...|:.|.. :||..||.|
  Rat   806 GPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACI-----EEDGKLYLC-VSSPTIKDK 864

  Fly   663 DVEVIPWIIADSNFVRSSSQKLDPTKTVFVGALHGKLTAEGLGNIMDDLFDGVLYAGIDTD-KYK 726
            .|::.||.::||:||...||.|||.||:|||.:...|.|..|..|||.|:.||.||||||| :.|
  Rat   865 PVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELK 929

  Fly   727 YPIGSGRVTFSNFRSYMKAVSAAFIEIRTTKFTKKVQVDPY-LEDALC-----SICGVQHGPYYC 785
            ||.|:|||.|||.:||:.|:||.|::::.....|:|:|.|| |:|.:|     :.||.:..|::|
  Rat   930 YPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFC 994

  Fly   786 RELSCFRYFCRSCWQWQHSCDIVKNHKPLTR 816
            ..::|.:|:|..||...||....:.||||.:
  Rat   995 ANVTCLQYYCEFCWANIHSRAGREFHKPLVK 1025

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
orb	NP_524460.2	RRM1_CPEB1	574..674	CDD:410122	37/101 (37%)
		RRM2_CPEB1	685..768	CDD:410124	44/84 (52%)
		CEBP_ZZ	762..817	CDD:465105	22/61 (36%)
Cpeb2	XP_038948724.1	RRM1_CPEB2_like	782..873	CDD:410123	36/96 (38%)
		RRM2_CPEB2_like	890..970	CDD:410125	40/79 (51%)
		CEBP_ZZ	965..1026	CDD:465105	22/61 (36%)