Protein Alignment orb and cpb-3

DIOPT Version :9

• Sequence 1: NP_001262870.1
• Gene: orb / 42752
• FlyBaseID: FBgn0004882
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: NP_491680.2
• Gene: cpb-3 / 172244
• WormBaseID: WBGene00000772
• Length: 745
• Species: Caenorhabditis elegans
• Alignment Length: 678
• Identity: 181/678 - (26%)
• Similarity: 291/678 - (42%)
• Gaps: 178/678 - (26%)

  Fly   251 KAFQRTNISFDCSAPLSP--------STPTSIYN--RSFHSSPLVSDSSNSSSGIG---LSMDSI 302
            |:.:|.| ....|..|||        .||.::|:  :.:|.|..|..:...:..:|   ||.|..
 Worm    19 KSTERKN-KIPPSLKLSPVESVGEKSPTPATVYDLFKKYHKSDSVKPTEEDNMNVGFDKLSTDEK 82

  Fly   303 NMFYNQQQQQQQPEQQGYTSLGNSMGSGLGLSLANAS---------TRSNSPESQNSSN------ 352
            |.|..:.|.         .::|:...|.:..|..:.:         :|..|.|..||||
 Worm    83 NGFLRKLQM---------LTVGSKKSSKVDESTPSPANRLLKKIVPSRRTSTEHPNSSNRMHIFG 138

  Fly   353 --STTEQNLLDMINLLSVNSNKIPHQQQQQ-----QQQQQQQQQQQQQNQQQLQVQQQHQLQQQF 410
              .||::         |::|.:...:::..     ::..:|::...:.|......:...:.::..
 Worm   139 SSRTTKK---------SIDSERNSQRKKSARRLNFERDAEQKKDSTKTNNSSFVAEMTREYEKIV 194

  Fly   411 V-------------NLNRNYEQQISANLGSQQHGFEHNGVGVGASSSGNENCFSQYNLENITSVD 462
            :             ||.||....:.....|.|.||..:   ..:|.|.:.|.|.  :.|:.||.:
 Worm   195 ISKGAPVPINKANRNLYRNPRGSLETPTDSPQKGFSSS---TESSPSDSMNQFP--SREHFTSAN 254

  Fly   463 MELAKLQNLQRINTLKLLHAQAQQMPLINQLLQSYAGNAIGSVGGSNLGNLMSAGGSSLMTEMAG 527
                                  ::.|:..:..|...||
 Worm   255 ----------------------EESPMKRKNFQQEHGN--------------------------- 270

  Fly   528 NVGGIITTNDGHLDRVAKFYKSSAALCDATCTWSGHLPPRSHRMLNYSPKVFLGGIPWDISEQSL 592
                                |:.    |:..||.|.||||.:....:|.|:|:||:||||:|.:|
 Worm   271 --------------------KNR----DSDATWFGELPPRDYTSPTFSRKIFVGGVPWDITEAAL 311

  Fly   593 IQIFKPFGSIKVEWPGKEQQ---------------AAQPK-------GYVYIIFESDKQVKALLS 635
            ...|..|||..|||||:|.:               .||.|       ||||:|||.::.|.:||.
 Worm   312 KDSFGEFGSCAVEWPGQEARYRSGQSNLAPSNGSLRAQTKYTGQAATGYVYMIFEDERAVASLLH 376

  Fly   636 ACVLQVDDSHCGRNYFFKISSRRIKS---KDVEVIPWIIADSNFVRSSS---QKLDPTKTVFVGA 694
            .|..::..:   ..::|||.::|.||   :.|::|||:.:||.|....:   ..::|.:||||||
 Worm   377 ECSQEIGGA---GEWYFKIRAQRSKSTEIRQVQIIPWVTSDSMFCEDDTLLETGIEPKRTVFVGA 438

  Fly   695 LHGKLTAEGLGNIMDDLFDGVLYAGIDTDKYKYPIGSGRVTFSNFRSYMKAVSAAFIEIRTTKFT 759
            |||.:||:.|.:||:|.|..|....:||||:|||||||||||....:|.||:...::.:.|:||.
 Worm   439 LHGMMTAQVLHSIMEDCFGAVECVQLDTDKFKYPIGSGRVTFREHGAYFKAIEMGYLHVYTSKFR 503

  Fly   760 KKVQVDPYLEDALCSICGVQHGPYYCRELSCFRYFCRSCWQWQHSCDIVKN-HKP-LTRNSKSQS 822
            |:||:||:||...|.:|..|....:||..:||:|:|.:||...|..|..:. |.| :..:|.|::
 Worm   504 KRVQIDPFLESTCCMVCNSQSAHCFCRNKNCFKYYCHNCWALDHGKDDDQEVHIPVIVPSSASKA 568

  Fly   823 LVGIGPSSSNVSLPFSGQRSIRDNRMGN 850
            ..|.....|.||...|.:....::::.|
 Worm   569 FPGATTRRSQVSSSLSLKNGSNNSQVNN 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
orb	NP_001262870.1	CEBP1_N	<540..570	CDD:292978	9/29 (31%)
		RRM1_CPEB1	574..674	CDD:241167	45/124 (36%)
		RRM2_CPEB1	685..770	CDD:241169	45/84 (54%)
		CEBP_ZZ	762..817	CDD:292976	21/56 (38%)
cpb-3	NP_491680.2	RRM1_CPEBs	295..412	CDD:240890	44/119 (37%)
		RRM2_CPEB1	429..514	CDD:241169	45/84 (54%)
		CEBP_ZZ	506..560	CDD:292976	21/53 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166030
Domainoid	1	1.000	91	1.000	Domainoid score	I4899
eggNOG	1	0.900	-	-		E1_KOG0129
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5016
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005701
OrthoInspector	1	1.000	-	-		oto20225
orthoMCL	1	0.900	-	-		OOG6_107196
Panther	1	1.100	-	-	LDO	PTHR12566
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5171
SonicParanoid	1	1.000	-	-		X4096
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.680