Protein Alignment orb and Cpeb1

DIOPT Version :10

• Sequence 1: NP_524460.2
• Gene: orb / 42752
• FlyBaseID: FBgn0004882
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: XP_011249086.1
• Gene: Cpeb1 / 12877
• MGIID: 108442
• Length: 600
• Species: Mus musculus
• Alignment Length: 678
• Identity: 243/678 - (35%)
• Similarity: 349/678 - (51%)
• Gaps: 137/678 - (20%)

  Fly   193 ASAAAAAAAAAGDGAQLSANAAAYAPLTPSSTHSSASPG-TKSNFDYFQFENVAQSNPLKAFQRT 256
            |..|..|.:..|:...|.....:.:|..........:.| .|..:|..:...::..:....|:|.
Mouse    10 APRAGRALSKPGEVTWLHTFDCSRSPSPEGGPGQEEAAGRIKDCWDNQEVPALSTCSNANIFRRI 74

  Fly   257 NISFDCSAPLSPSTPTSIYNRSFHSSPLVSDSSNSSSGIGLSMDSINMFYNQQQQQQQPEQQGYT 321
            |...|.|...|....|.| ||..|.. |.:|..:|...:...|    :|....|:..:
Mouse    75 NAILDDSLDFSKVCTTPI-NRGIHDQ-LPADFQDSEETVTSRM----LFPTSAQESPR------- 126

  Fly   322 SLGNSMGSGLG---LSLANASTRSNSPESQNSSNSTTEQNLLDMI-NLLSVNSNKIPHQQQQQQQ 382
            .|.::.|..||   |||.......::.:|.:|:.|:| |::|.|: |.|.....|.|
Mouse   127 GLPDANGLCLGLQSLSLTGWDRPWSTQDSDSSAQSST-QSVLSMLQNPLGNVLGKAP-------- 182

  Fly   383 QQQQQQQQQQQNQQQLQVQQQHQLQQQFVNLNRNYEQQISANLGSQQHGFEHNGVGVGA------ 441
                                     ..|::|:         .|||....|....|. |:
Mouse   183 -------------------------LSFLSLD---------PLGSDLDKFPAPSVR-GSRLDTRP 212

  Fly   442 -----SSSGNENCFSQYNLENITSVDMELAKLQNLQRINTLKLLHAQAQQMPLINQLLQSYAGN- 500
                 |||.:::     :....:|....|:.|     |::|::    :..:|.:     |..||
Mouse   213 ILDSRSSSPSDS-----DTSGFSSGSDHLSDL-----ISSLRI----SPPLPFL-----SMTGNG 258

  Fly   501 ------------------AIGSVGGSNLGNLMSAGGSSLMT--EMAGNVGGIITTNDGHLDRVAK 545
                              |:.:|..|.........|:|:..  ::.|     ...:...::|.|:
Mouse   259 PRDPLKMGVGSRMDQEQAALAAVAPSPTSAPKRWPGASVWPSWDLLG-----APKDPFSIEREAR 318

  Fly   546 FYKSSAALCDATCTWSGHLPPRSHRMLNYSPKVFLGGIPWDISEQSLIQIFKPFGSIKVEWPGKE 610
            .::.:||:.:|||||||.||||:::...||.||||||:||||:|..|:..|:.|||:.||||||:
Mouse   319 LHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKD 383

  Fly   611 -------QQAAQPKGYVYIIFESDKQVKALLSACVLQVDDSHCG------RNYFFKISSRRIKSK 662
                   .:...||||||::||.:|.|:|||.||      ||..      ..|:||:||||::.|
Mouse   384 GKHPRCPPKGNMPKGYVYLVFELEKSVRALLQAC------SHDPLSPDGLSEYYFKMSSRRMRCK 442

  Fly   663 DVEVIPWIIADSNFVRSSSQKLDPTKTVFVGALHGKLTAEGLGNIMDDLFDGVLYAGIDTDKYKY 727
            :|:||||::||||||.|.||:|||::|||||||||.|.||.|..|::|||.||:||||||||:||
Mouse   443 EVQVIPWVLADSNFVWSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKY 507

  Fly   728 PIGSGRVTFSNFRSYMKAVSAAFIEIRTTKFTKKVQVDPYLEDALCSICGVQHGPYYCRELSCFR 792
            |||||||||:|.|||:|||:|||:||:|||||||||:||||||:||.||..|.||::||:..||:
Mouse   508 PIGSGRVTFNNQRSYLKAVTAAFVEIKTTKFTKKVQIDPYLEDSLCLICSSQPGPFFCRDQVCFK 572

  Fly   793 YFCRSCWQWQHSCDIVKNHKPLTRNSKS 820
            |||||||.|:||.:.:::|.||.||.|:
Mouse   573 YFCRSCWHWRHSMEGLRHHSPLMRNQKN 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
orb	NP_524460.2	RRM1_CPEB1	574..674	CDD:410122	55/112 (49%)
		RRM2_CPEB1	685..768	CDD:410124	63/82 (77%)
		CEBP_ZZ	762..817	CDD:465105	32/54 (59%)
Cpeb1	XP_011249086.1	CEBP1_N	44..345	CDD:465107	79/381 (21%)
		RRM1_CPEB1	347..454	CDD:410122	55/112 (49%)
		RRM2_CPEB1	465..548	CDD:410124	63/82 (77%)
		CEBP_ZZ	542..597	CDD:465105	32/54 (59%)