DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13827 and PEX11G

DIOPT Version :9

Sequence 1:	NP_001247263.1	Gene:	CG13827 / 42751	FlyBaseID:	FBgn0039068	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_542393.1	Gene:	PEX11G / 92960	HGNCID:	20208	Length:	241	Species:	Homo sapiens

Alignment Length:	211	Identity:	63/211 - (29%)
Similarity:	112/211 - (53%)	Gaps:	10/211 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KVMKALCYSAKLVAGYHAKRNP---ELAKRYATASSRISGARATLRLIDDIPMIQYALEYGLGEN 85
            ::::.|.|..:||.|...::.|   |:..|....|:::|..|..|||.||:.|..|..:||||..
Human    19 RLIRVLGYCCQLVGGVLVEQCPARSEVGTRLLVVSTQLSHCRTILRLFDDLAMFVYTKQYGLGAQ 83

  Fly    86 EPDRVMQVLGVTANIVDLLYYPIEKVCWLAEHKIVDVKNADNWDNVNSIFWVLSVYLNLMRTMRN 150
            |.|..::.:.|..|:.|.||||.|.|.|.|:.:::.| ::..|..:::..|.||:.|.:.|::..
Human    84 EEDAFVRCVSVLGNLADQLYYPCEHVAWAADARVLHV-DSSRWWTLSTTLWALSLLLGVARSLWM 147

  Fly   151 FSLNQEKLNR-----TNNINELDVKTL-TKHRLEMVSIVRISLDFVHAVSTLPKGYLWGGKLSTL 209
            ....:::|..     |:.:.....:.: .:.:.|.:|::....|..:||..||:|.||.|:....
Human   148 LLKLRQRLRSPTAPFTSPLPRGKRRAMEAQMQSEALSLLSNLADLANAVHWLPRGVLWAGRFPPW 212

  Fly   210 QVGAIGTLSAGLGIYQ 225
            .||.:||:|:.|.:||
Human   213 LVGLMGTISSILSMYQ 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13827	NP_001247263.1	PEX11	24..226	CDD:283335	63/211 (30%)
PEX11G	NP_542393.1	PEX11	4..229	CDD:310329	63/211 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160365
Domainoid	1	1.000	107	1.000	Domainoid score	I6547
eggNOG	1	0.900	-	-		E1_KOG4186
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12298
Inparanoid	1	1.050	107	1.000	Inparanoid score	I4934
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50137
OrthoDB	1	1.010	-	-		D1522222at2759
OrthoFinder	1	1.000	-	-		FOG0006578
OrthoInspector	1	1.000	-	-		otm41454
orthoMCL	1	0.900	-	-		OOG6_105118
Panther	1	1.100	-	-	LDO	PTHR20990
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5235
SonicParanoid	1	1.000	-	-		X6326
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800