DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wda and TEX1

DIOPT Version :9

Sequence 1:	NP_651136.1	Gene:	wda / 42750	FlyBaseID:	FBgn0039067	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_014146.1	Gene:	TEX1 / 855468	SGDID:	S000005197	Length:	422	Species:	Saccharomyces cerevisiae

Alignment Length:	427	Identity:	88/427 - (20%)
Similarity:	149/427 - (34%)	Gaps:	116/427 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 SATEQILK--------SQVELPRFLRISERSRG-LTSAHLDPSECHMLAGFDNSAVQLWQLNQSY 424
            |.|.:.|:        |.:|..||:.:|.||.. .||..:.|:|...|              :.:
Yeast    22 SVTSKYLQSTFSKGNTSHIEDKRFIHVSSRSHSRFTSTPITPNEILSL--------------KFH 72

  Fly   425 CRGKSF-YRRYPQKRCPWELNN--------------CANQEEETD--------------EDSSDE 460
            ..|.|. |.|.......|.:.:              |.:.:..||              .:||:.
Yeast    73 VSGSSMAYSRMDGSLTVWFIKDASFDKSVEVYIPDCCGSDKLATDLSWNPTSLNQIAVVSNSSEI 137

  Fly   461 DVKCSEEERRERNRARHCKYADNS------YNEYGGFQLRGHTKGVTDVRFSAHYPLMYSVSKDA 519
            .:....|:....::.|.......:      |:..|.:.|.. ||        :....::.|.||.
Yeast   138 SLLLINEKSLTASKLRTLSLGSKTKVNTCLYDPLGNWLLAA-TK--------SEKIYLFDVKKDH 193

  Fly   520 TMRCWRAHNLHCAAIYRSHNYPIWCLDESPVGQYVVTGSKDLSARLWSLEKEHALIIYA----GH 580
            :..|    :|:.:.|.:..|..::.|..|..|.::..|.|  |..|..|:.:|.::...    .|
Yeast   194 SSVC----SLNISDISQEDNDVVYSLAWSNGGSHIFIGFK--SGYLAILKAKHGILEVCTKIKAH 252

  Fly   581 TQDVECVAFHPNGNYIATGSADHSVRLWCATSGKLMRVFADCRQAVTQLAFSPDGKMLAAAGEET 645
            |..:..:...|.|....|||.|.:..:|...|.....:..|...|||.|.....||:|....|:.
Yeast   253 TGPITEIKMDPWGRNFITGSIDGNCYVWNMKSLCCELIINDLNSAVTTLDVCHLGKILGICTEDE 317

  Fly   646 KVRIFDLAAGAQLAELKDHSASISSL------------SW----------STH----NRHLATAC 684
            .|..:||.:|..|     ||.|:::.            ||          |.|    .::|.|..
Yeast   318 MVYFYDLNSGNLL-----HSKSLANYKTDPVLKFYPDKSWYIMSGKNDTLSNHFVKNEKNLITYW 377

  Fly   685 SDGTLRLWDIKKLSPMSDNSSAGSS----SSATTNRV 717
            .|    ::|...:.....|:..|::    :|..|:|:
Yeast   378 KD----MFDNTMIEKRRKNNGGGNNHNKRTSKNTDRI 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wda	NP_651136.1	TAF5_NTD2	104..273	CDD:298747
		WD40	324..>700	CDD:225201	83/404 (21%)
		WD40	491..700	CDD:238121	54/238 (23%)
		WD40 repeat	501..537	CDD:293791	6/35 (17%)
		WD40 repeat	542..578	CDD:293791	9/35 (26%)
		WD40 repeat	585..619	CDD:293791	8/33 (24%)
		WD40 repeat	626..662	CDD:293791	12/35 (34%)
TEX1	NP_014146.1	WD40	1..>374	CDD:225201	79/385 (21%)
		WD40 repeat	66..109	CDD:293791	6/56 (11%)
		WD40 repeat	116..158	CDD:293791	6/41 (15%)
		WD40 repeat	163..205	CDD:293791	10/54 (19%)
		WD40 repeat	213..249	CDD:293791	9/37 (24%)
		WD40 repeat	256..290	CDD:293791	8/33 (24%)
		WD40 repeat	298..336	CDD:293791	15/42 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810