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Protein Alignment wda and MDV1

DIOPT Version :9

Sequence 1:	NP_651136.1	Gene:	wda / 42750	FlyBaseID:	FBgn0039067	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_012423.1	Gene:	MDV1 / 853332	SGDID:	S000003648	Length:	714	Species:	Saccharomyces cerevisiae

Alignment Length:	534	Identity:	114/534 - (21%)
Similarity:	180/534 - (33%)	Gaps:	172/534 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 VENEQRAFSEDHLLGLTDDLEGEDGEDDVVSKPAVTLNTRGDIRPSKSLTEKSNRKRPAEEPNIM 336
            :||.:|...:      |:...|..|..||:||    .|.|.:|.              .|.||..
Yeast   163 IENTERLNYD------TNGTSGTVGAKDVMSK----TNERDEIH--------------TELPNFQ 203

  Fly   337 LETDIKQEVETDE-------------------SAELSKLQLN--------IDACLDTLKSATEQI 374
            ....|...|||.:                   |.|...:|.|        |:..::.|:...|::
Yeast   204 DSFLIPPGVETKKISSSYSPSALKSFSQTLVNSLEFLNIQKNSTLSEIRDIEVEVENLRQKKEKL 268

  Fly   375 LK--SQVELPRFL------RISERSRGLTSAHLDPSECHMLAGFDNSAVQLWQLNQSYCRGKSFY 431
            |.  :.:|..:.|      :|.:|...|....|:..|    |..|.:|           ......
Yeast   269 LGKIANIEQNQLLLEDNLKQIDDRLDFLEEYGLEVIE----ANSDENA-----------EDDGMS 318

  Fly   432 RRYPQKRCPWELNNCANQEEETDEDSSDEDVKCSEEERRERNRARHCKYADNSYNEYGGFQLRG- 495
            .|...|      |:....|..|.|..|.|   .|....|.|.:.|.    |||.|..|.|..:.
Yeast   319 ERKALK------NDAIRNEGVTTESISSE---ASNLPPRRRQQLRD----DNSLNRLGAFYSKSK 370

  Fly   496 --HTKGVTDVR------------FSAHYPLMYSVSKDATMRCWRAHNLHCAAIYRSHNYPIWCLD 546
              |.|.....:            .|.|...:..:..||..      ...|.|.|..|...||.|.
Yeast   371 KRHRKSFPTFQQLYEPGTKIGSIMSTHDDFLTCLDFDAPF------GTLCTAGYLDHTVKIWDLS 429

  Fly   547 -ESPVGQY------------------VVTGSKDLSARLWSLEKEHALI----------------- 575
             ::.:|:.                  :|||.:|.:.:||:|.....|.
Yeast   430 KQNKIGELAGHLATINCMQINRDYGTLVTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHIDSPC 494

  Fly   576 --IYAGHTQDVECVAFHPNGNYIATGSADHSVRLWCATSGKLMRV----FADCRQAVTQLAFSPD 634
              .:..||.:|..::..|  :::.:||.|.::|.|...|||.::.    ||:.....|.:..|..
Yeast   495 VHTFEAHTDEVTALSLDP--SFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKS 557

  Fly   635 GKM------------------LAAAGEETKVRIFDLAAGAQLAELKDHSASISSLSWSTHNRHLA 681
            ..:                  ||...::..||::||.:|..:..||.|:.:|:||.:.  :..|.
Yeast   558 TLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKFD--SACLV 620

  Fly   682 TACSDGTLRLWDIK 695
            |...|.|:|:||::
Yeast   621 TGSYDRTVRIWDLR 634

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.