DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wda and WDR61

DIOPT Version :9

Sequence 1:NP_651136.1 Gene:wda / 42750 FlyBaseID:FBgn0039067 Length:743 Species:Drosophila melanogaster
Sequence 2:NP_001290176.1 Gene:WDR61 / 80349 HGNCID:30300 Length:305 Species:Homo sapiens


Alignment Length:209 Identity:54/209 - (25%)
Similarity:102/209 - (48%) Gaps:10/209 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   491 FQLRGHTKGVTDVRFSAHYPLMYSVSKDATMRCWRAHNLHCAAIYRSHNYPIWCLDESPVGQYVV 555
            :.|.||..||..|..|...|:..|.|.||.:|.|...|........:.....|.|..||..||:.
Human    58 WSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLA 122

  Fly   556 TGSKDLSARLWSLE---KEHALIIYAGHTQD--VECVAFHPNGNYIATGSADHSVRLWCATSGKL 615
            ||:......::.:|   ||::|     .|:.  :..:|:.|:|.|:|:|:.|..:.::...:|||
Human   123 TGTHVGKVNIFGVESGKKEYSL-----DTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKL 182

  Fly   616 MRVFADCRQAVTQLAFSPDGKMLAAAGEETKVRIFDLAAGAQLAELKDHSASISSLSWSTHNRHL 680
            :.........:..|.||||.::|..|.::..::|:|:........|..|::.:.::::...:.|.
Human   183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHF 247

  Fly   681 ATACSDGTLRLWDI 694
            .::.||.::::||:
Human   248 VSSSSDKSVKVWDV 261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdaNP_651136.1 TAF5_NTD2 104..273 CDD:298747
WD40 324..>700 CDD:225201 54/209 (26%)
WD40 491..700 CDD:238121 54/209 (26%)
WD40 repeat 501..537 CDD:293791 10/35 (29%)
WD40 repeat 542..578 CDD:293791 12/38 (32%)
WD40 repeat 585..619 CDD:293791 10/33 (30%)
WD40 repeat 626..662 CDD:293791 9/35 (26%)
WDR61NP_001290176.1 WD40 13..302 CDD:238121 54/209 (26%)
WD 1 14..57
WD40 repeat 19..62 CDD:293791 1/3 (33%)
WD 2 62..101 14/38 (37%)
WD40 repeat 68..105 CDD:293791 10/36 (28%)
WD 3 104..143 11/38 (29%)
WD40 repeat 110..146 CDD:293791 12/40 (30%)
WD 4 146..187 11/40 (28%)
WD40 repeat 152..188 CDD:293791 10/35 (29%)
WD 5 188..227 9/38 (24%)
WD40 repeat 193..229 CDD:293791 9/35 (26%)
WD 6 230..269 6/32 (19%)
WD40 repeat 236..271 CDD:293791 5/26 (19%)
WD 7 272..305
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4155
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.