DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wda and DCAF10

DIOPT Version :9

Sequence 1:	NP_651136.1	Gene:	wda / 42750	FlyBaseID:	FBgn0039067	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_077321.3	Gene:	DCAF10 / 79269	HGNCID:	23686	Length:	559	Species:	Homo sapiens

Alignment Length:	152	Identity:	41/152 - (26%)
Similarity:	66/152 - (43%)	Gaps:	39/152 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   588 AFHPNGNYIATGSADHSVRLWCATSGKLMRVFADCRQAVTQLAFSPDGKMLAAAGEETKVRIFDL 652
            :.||         || ||.|...|.|           ||..|.:||||.:|..|.|:|:|.:||.
Human   154 SIHP---------AD-SVYLSTRTHG-----------AVFNLEYSPDGSVLTVACEQTEVLLFDP 197

  Fly   653 AAGAQLAELKD-HSASISSLSWSTHNRHLATACSDGTLRLWDIKKLSPMSDNSSAGSSSSATTNR 716
            .:...:..|.: |...::::.: ..||..||...|.|:.|||::||:                .:
Human   198 ISSKHIKTLSEAHEDCVNNIRF-LDNRLFATCSDDTTIALWDLRKLN----------------TK 245

  Fly   717 VLTVNSSCQRLVDVFYGTSKTL 738
            |.|::.....:.::.|.|:..|
Human   246 VCTLHGHTSWVKNIEYDTNTRL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wda	NP_651136.1	TAF5_NTD2	104..273	CDD:298747
		WD40	324..>700	CDD:225201	36/112 (32%)
		WD40	491..700	CDD:238121	36/112 (32%)
		WD40 repeat	501..537	CDD:293791
		WD40 repeat	542..578	CDD:293791
		WD40 repeat	585..619	CDD:293791	9/30 (30%)
		WD40 repeat	626..662	CDD:293791	13/35 (37%)
DCAF10	NP_077321.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..119
		WD40	<164..319	CDD:295369	34/132 (26%)
		WD 1	166..205		16/49 (33%)
		WD40	<171..>334	CDD:225201	31/114 (27%)
		WD40 repeat	172..207	CDD:293791	12/34 (35%)
		WD 2	209..247		12/54 (22%)
		WD40 repeat	214..250	CDD:293791	13/52 (25%)
		WD 3	251..290		3/17 (18%)
		WD40 repeat	256..282	CDD:293791	3/12 (25%)
		WD 4	296..335
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	350..396
		WD 5	408..448
		WD 6	470..508
		WD40	517..555	CDD:197651
		WD 7	526..559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900