DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wda and Wdsub1

DIOPT Version :9

Sequence 1:NP_651136.1 Gene:wda / 42750 FlyBaseID:FBgn0039067 Length:743 Species:Drosophila melanogaster
Sequence 2:NP_001366327.1 Gene:Wdsub1 / 72137 MGIID:1919387 Length:475 Species:Mus musculus


Alignment Length:218 Identity:60/218 - (27%)
Similarity:95/218 - (43%) Gaps:23/218 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   493 LRGHTKGVTDVRFSAHYPLMYSVSKDATMRCWRAHNLHCAAI----YRSHNYPIWCLDESPVGQY 553
            |..|...|:...|||  .|:.:.|.|.|:|.:...:.  |.:    .:.|.|.:.|...||.|..
Mouse     8 LADHGDDVSCCAFSA--ALLATCSLDKTIRLYSLSDF--AELPYSPLKFHTYAVHCCCFSPSGHV 68

  Fly   554 VVTGSKDLSARLWSLEKEHALIIY---AGHTQDVECVAFHPNGNYIATGSADHSVRLWCATSGKL 615
            :.:.|.|.:..|||....|.|.:.   .|....|.|  |.|:..|:|:|:||.|:.||.|.:.||
Mouse    69 LASCSTDGTTVLWSSHSGHTLTVLEQPGGSPVRVCC--FSPDSAYLASGAADGSIALWNAQTYKL 131

  Fly   616 MRVFADCRQAVTQLAFSPDGKMLAAAGEETKVRIFDLAAGAQLAELKDHSASISSLSWST----- 675
            .|..:....::...||||||.:.........:.::|.......:| |.|...|:..|:|:     
Mouse   132 YRCGSVKDSSLVACAFSPDGGLFVTGSSGGDLTVWDDRMRCLHSE-KAHDLGITCCSFSSQPLSG 195

  Fly   676 ----HNRHLATACSDGTLRLWDI 694
                .:..||:...|..::||.:
Mouse   196 GEGLQSYQLASCGQDCEIKLWAV 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdaNP_651136.1 TAF5_NTD2 104..273 CDD:298747
WD40 324..>700 CDD:225201 60/218 (28%)
WD40 491..700 CDD:238121 60/218 (28%)
WD40 repeat 501..537 CDD:293791 9/39 (23%)
WD40 repeat 542..578 CDD:293791 11/38 (29%)
WD40 repeat 585..619 CDD:293791 15/33 (45%)
WD40 repeat 626..662 CDD:293791 8/35 (23%)
Wdsub1NP_001366327.1 WD40 4..308 CDD:238121 60/218 (28%)
WD 1 10..47 11/40 (28%)
WD40 repeat 16..52 CDD:293791 9/39 (23%)
WD 2 52..91 13/38 (34%)
WD40 repeat 57..93 CDD:293791 11/35 (31%)
WD 3 95..134 16/40 (40%)
WD40 repeat 101..136 CDD:293791 16/36 (44%)
WD 4 137..176 7/38 (18%)
WD40 repeat 143..177 CDD:293791 8/34 (24%)
WD 5 178..227 9/41 (22%)
WD40 repeat 183..235 CDD:293791 8/36 (22%)
WD 6 236..275
WD40 repeat 241..264 CDD:293791
WD40 repeat 283..307 CDD:293791
SAM_WDSUB1 327..398 CDD:188904
U-box 403..475 CDD:398320
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4155
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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