DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wda and Wdr72

DIOPT Version :9

Sequence 1:NP_651136.1 Gene:wda / 42750 FlyBaseID:FBgn0039067 Length:743 Species:Drosophila melanogaster
Sequence 2:NP_001028672.2 Gene:Wdr72 / 546144 MGIID:3583957 Length:1114 Species:Mus musculus


Alignment Length:307 Identity:63/307 - (20%)
Similarity:100/307 - (32%) Gaps:96/307 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   493 LRGHTKGVTDVRFSAHYP----------LMYSVSKDATMRCWRAHNLHCAAIYRSHNYPIWCLDE 547
            ||||.:.||    |..||          .|.|..:.:.:..|        .|:.......:.|:.
Mouse   468 LRGHHQSVT----SLLYPHNLASKLDQSWMVSGDRGSYVILW--------DIFTEEILHTFFLEA 520

  Fly   548 SPV--------------GQYVVTGSKDLSARLWSLEKEHALIIYAGHTQDVECVAFHPNGNYIAT 598
            .||              ||.:.....|.|..|..||....|:....|...|..:.:||..|::..
Mouse   521 GPVTRLLMSPENLKRSDGQILCCVCGDHSVALLHLEGRRCLLRARKHLFPVRMIRWHPVENFLIV 585

  Fly   599 GSADHSVRLWCATSGKL--------MRVFADCRQAVTQLAFSPDGKMLAAAGEETKVRIFD---- 651
            |..|.||.:|...:|.|        .|:..:|......:...|   .|:.|.|..|.:..:    
Mouse   586 GCTDDSVYIWEIETGTLERHETGERARIILNCGDDAQLIRSEP---TLSVASETHKHKSIEQKSS 647

  Fly   652 --------------LAAGAQLAELKDHSASISSL----SWSTHNRHLATACSDGTLRLWDIKKL- 697
                          |.:..::|:........:.|    .||....|:.         |:|::.| 
Mouse   648 NSHQPGPVPCPSVQLESSCKVADASSVPRPFNVLPVKTKWSHIGFHVL---------LFDLENLV 703

  Fly   698 -----SPMSDNSSAGS---------SSSATTNRVLTV---NSSCQRL 727
                 :|:||...:||         :.|....:.||:   .:||..|
Mouse   704 ELLLPTPLSDVDPSGSFYGGDILRRAKSTVEKKTLTIRRNKASCSSL 750

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdaNP_651136.1 TAF5_NTD2 104..273 CDD:298747
WD40 324..>700 CDD:225201 52/266 (20%)
WD40 491..700 CDD:238121 52/266 (20%)
WD40 repeat 501..537 CDD:293791 8/45 (18%)
WD40 repeat 542..578 CDD:293791 11/49 (22%)
WD40 repeat 585..619 CDD:293791 11/41 (27%)
WD40 repeat 626..662 CDD:293791 7/53 (13%)
Wdr72NP_001028672.2 WD40 14..>191 CDD:392136
WD 1. /evidence=ECO:0000255 15..54
WD40 repeat 20..60 CDD:293791
WD 2. /evidence=ECO:0000255 60..102
WD40 repeat 66..107 CDD:293791
WD40 repeat 112..151 CDD:293791
WD40 repeat 160..206 CDD:293791
WD 3. /evidence=ECO:0000255 160..197
WD 4. /evidence=ECO:0000255 327..373
WD 5. /evidence=ECO:0000255 413..452
WD40 418..>606 CDD:392136 36/149 (24%)
WD40 repeat 419..470 CDD:293791 1/1 (100%)
WD 6. /evidence=ECO:0000255 470..515 11/56 (20%)
WD40 repeat 475..516 CDD:293791 9/52 (17%)
WD 7. /evidence=ECO:0000255 566..605 12/38 (32%)
WD40 repeat 571..597 CDD:293791 9/25 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 634..658 2/23 (9%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 749..798 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4155
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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