DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wda and wdr32

DIOPT Version :9

Sequence 1:NP_651136.1 Gene:wda / 42750 FlyBaseID:FBgn0039067 Length:743 Species:Drosophila melanogaster
Sequence 2:NP_998111.2 Gene:wdr32 / 405882 ZFINID:ZDB-GENE-040426-2314 Length:508 Species:Danio rerio


Alignment Length:260 Identity:62/260 - (23%)
Similarity:90/260 - (34%) Gaps:87/260 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   449 QEEETDEDSSDED----VKCSEEERRE----RNRARHCKYADNSYNEYGGFQLRGHTKGVTDVRF 505
            :|||.:|:.||||    ...|.:..||    :..:|....||.......|...||  .|..|..|
Zfish    21 EEEEEEEEDSDEDRGSTRPASPQATRECAGTQGSSRPEVTADGGTGSASGSGCRG--SGACDSLF 83

  Fly   506 SAHYPLMYSVSKDATMRCWRAHNLHCAAIYRSHNYPIW-CLDESPVGQYVVTGSKDLSARLWSLE 569
            |                                    | |..:...|.| |..::|....:..| 
Zfish    84 S------------------------------------WICRRKIRRGPY-VDPARDHFRTMTRL- 110

  Fly   570 KEHALIIYAGHTQDVECVAFHPNGNYIATGSADHSVRLWCATSGKLMRVFADCRQAVTQLAFSPD 634
                                     |.:...|..||.|...|.|           ||..|.:|||
Zfish   111 -------------------------YSSMSPAADSVNLSTQTHG-----------AVFNLEYSPD 139

  Fly   635 GKMLAAAGEETKVRIFDLAAGAQLAELKD-HSASISSLSWSTHNRHLATACSDGTLRLWDIKKLS 698
            |.:|..|.|:|:|.:||..:...:..|.: |...::::.: ..||..||...|.|:.|||::||:
Zfish   140 GSVLTVACEQTEVLLFDPVSSRHIKTLVEAHEDCVNNIRF-LDNRLFATCSDDTTIALWDLRKLN 203

  Fly   699  698
            Zfish   204  203

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdaNP_651136.1 TAF5_NTD2 104..273 CDD:298747
WD40 324..>700 CDD:225201 62/260 (24%)
WD40 491..700 CDD:238121 47/210 (22%)
WD40 repeat 501..537 CDD:293791 3/35 (9%)
WD40 repeat 542..578 CDD:293791 7/36 (19%)
WD40 repeat 585..619 CDD:293791 7/33 (21%)
WD40 repeat 626..662 CDD:293791 13/35 (37%)
wdr32NP_998111.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..75 15/53 (28%)
WD 1 126..165 16/49 (33%)
WD40 <129..279 CDD:295369 28/87 (32%)
WD40 <131..>294 CDD:225201 26/74 (35%)
WD40 repeat 132..167 CDD:293791 12/34 (35%)
WD 2 169..207 12/36 (33%)
WD40 repeat 174..210 CDD:293791 11/31 (35%)
WD 3 211..250
WD40 repeat 216..242 CDD:293791
WD 4 256..295
WD40 repeat 261..288 CDD:293791
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 307..343
WD 5 356..396
WD 6 419..457
WD 7 475..508
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4155
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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