DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wda and rec14

DIOPT Version :9

Sequence 1:	NP_651136.1	Gene:	wda / 42750	FlyBaseID:	FBgn0039067	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	NP_596145.1	Gene:	rec14 / 2540221	PomBaseID:	SPBC32F12.02	Length:	302	Species:	Schizosaccharomyces pombe

Alignment Length:	327	Identity:	71/327 - (21%)
Similarity:	126/327 - (38%)	Gaps:	89/327 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 SAH-LDPSECHMLAGFDNSAVQLWQLNQSYCRGKSFYRRYPQKRCPWELNNCANQ-EEETD---- 454
            :|| .|....:::||      .||..:     |.|..::       |.:.:..:. .||.|
pombe    13 NAHQADIYSLNVVAG------NLWSAS-----GDSKIKK-------WSIGDAEHSLVEEIDTPHK 59

  Fly   455 ------EDSSDEDVKCSEEERRERNRARHCKYADNSY------NEYGGFQLRGHTKGVTDVRFSA 507
                  ..|.||:|..|            |.:..:.|      ||:            .|:..:|
pombe    60 LGVHHLATSLDENVVVS------------CGFGQDVYVWNPETNEF------------RDLGNNA 100

  Fly   508 HYPLMYSVSKDATMRCWRAHNLHCAAIYRSHNYPIWCLDESPVGQYVVTGSKDLSARLWSLEKEH 572
            .:|          ..||.:                 |:  ||.||.:...|.|....:|....:.
pombe   101 QHP----------SECWSS-----------------CI--SPDGQTIAFTSVDGRIAVWDNPSDC 136

  Fly   573 ALIIYAGHTQDVECVAFHPNGNYIATGSADHSVRLWCATSGKLMRVFADCRQAVTQLAFSPDGKM 637
            .:.......:...|:.:.|||.:|.:|.....:.|....:|:|..|.:.....|..:||||...:
pombe   137 KISELDTKGKFGLCIDYSPNGRFIVSGHQTGQLFLISTETGRLFHVLSGHTSPVRSVAFSPGSTL 201

  Fly   638 LAAAGEETKVRIFDLAAGAQLAELKDHSASISSLSWSTHNRHLATACSDGTLRLWDIKKLSPMSD 702
            |||||:...:.|:|:.:|.|:.:|:.|:|.|.:::::.....|.:|..:|.:::|||..:..:|.
pombe   202 LAAAGDSKMITIYDVLSGDQVGQLRGHAAWIFAVAFNPVGDLLLSADVEGKIKIWDIDTMECIST 266

  Fly   703 NS 704
            .|
pombe   267 QS 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wda	NP_651136.1	TAF5_NTD2	104..273	CDD:298747
		WD40	324..>700	CDD:225201	69/321 (21%)
		WD40	491..700	CDD:238121	47/208 (23%)
		WD40 repeat	501..537	CDD:293791	5/35 (14%)
		WD40 repeat	542..578	CDD:293791	8/35 (23%)
		WD40 repeat	585..619	CDD:293791	9/33 (27%)
		WD40 repeat	626..662	CDD:293791	14/35 (40%)
rec14	NP_596145.1	WD40	5..>296	CDD:225201	71/327 (22%)
		WD40	15..297	CDD:238121	70/325 (22%)
		WD40 repeat	63..98	CDD:293791	10/58 (17%)
		WD40 repeat	103..142	CDD:293791	11/67 (16%)
		WD40 repeat	149..184	CDD:293791	10/34 (29%)
		WD40 repeat	190..226	CDD:293791	14/35 (40%)
		WD40 repeat	232..267	CDD:293791	8/34 (24%)
		WD40 repeat	274..296	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900