Protein Alignment EloA and eloa

DIOPT Version :10

• Sequence 1: NP_732846.1
• Gene: EloA / 42749
• FlyBaseID: FBgn0039066
• Length: 643
• Species: Drosophila melanogaster
• Sequence 2: NP_998620.1
• Gene: eloa / 406764
• ZFINID: ZDB-GENE-040426-2810
• Length: 622
• Species: Danio rerio
• Alignment Length: 683
• Identity: 193/683 - (28%)
• Similarity: 320/683 - (46%)
• Gaps: 118/683 - (17%)

  Fly     7 LLDVVRHYQRSIEKHGEDEQRLLHCITKLFNLPIKFEHLQETGIGKTVNALRK--ISGEVGVAAK 69
            :|:.|...|..:..: ::.::||..:.:|..||:..:.|.|||||||||:|||  .:||   |||
Zfish     5 ILEAVEKLQLRLGDN-QEPRKLLKTLKRLGELPMTVDILVETGIGKTVNSLRKHEYAGE---AAK 65

  Fly    70 TLVTKWKAMVAKED---PSIASTPTAIHNEEDSGKTKSSDEDP--------DQENKGG------- 116
            .||.|||.:|.::.   ||:....:.....|.:|..:..:..|        :|..:.|
Zfish    66 NLVAKWKKLVPEKSADRPSVKDGRSHSRISESAGHRRVRERSPVEPPLMEEEQHEEMGYQHGYSP 130

  Fly   117 -----NSSSGEDLNTSKHKSKHAKSTKHERSSSSRSHSKSRSDSDKKHKSSRHDKSKDRDKDREG 176
                 ..||.....:.:::|......:.....::..|||...:..::| :|:..:.::|.|.|.|
Zfish   131 SPPQYRHSSAPQYQSDEYESPPEDEPEPSPPPNNIRHSKPHKEPVREH-NSQDLRDQERRKQRPG 194

  Fly   177 QKEAKEHKEKKSNGEHKSKDSSKSSSSHKSSKSESHKSEHTKSKHEKDKTSHSELKEVKDKSSKH 241
            .:|.....:::..|          .:||             :|||::..:||      :.|..|.
Zfish   195 GEERTNRADREQQG----------GTSH-------------RSKHDRHLSSH------EGKREKK 230

  Fly   242 KSSSSKSSKRSHSPPRHEEESQKAKIPKVKSKSEEDSADGFDSSMGANFDDVLGLLNIPISSKKS 306
            ..|..||.:|...|...:|:.:..:.|.:          .|:|.:  .:|     ...|...||.
Zfish   231 GGSDGKSRERKEVPGPVDEDEEPYEAPTM----------SFESFL--TYD-----APTPTKKKKQ 278

  Fly   307 SSNSKSKFVAKPTAAPSSSALSAPTTAGSSKEALSTSSRPTSKKPELLASTAKLEPLDPNIALEL 371
            .|.........|:|:.|.|:.:..|::..||.:.|:||..|...||.......:.|..|:|  .|
Zfish   279 PSRPPQPPAPLPSASSSKSSKANGTSSKRSKPSSSSSSVTTPAVPEKRKKVVDVVPTLPDI--PL 341

  Fly   372 PTISNNYKPMPLNQTVMDVVFNQGGSHKAQASRYFNESEALAQGISSKTMRTK--IYSGVRTGQI 434
            |.|...|:|:|    .:|:........|...|   ||.|  ..|.:.:.:.:|  :|||.:|..:
Zfish   342 PAIQPFYRPLP----SIDLTPLSPQRRKVPVS---NEEE--DGGYTGRRLNSKMVVYSGSKTAYL 397

  Fly   435 LQVPSLFDLCTRVLQKNIDALEYTGGVPFEVLRPVLERATPQQLLNFEEYNPYLMDDSDVLWQQH 499
            .::.||::.|.||||.||.:::..||||||:|.|||||.||:||...|:.|....::||.||.:|
Zfish   398 PKMMSLYEQCIRVLQNNIGSIDEVGGVPFEILMPVLERCTPEQLYRIEQCNQSFTEESDDLWMKH 462

  Fly   500 VQRHCRSQRREEMETWREMFLRCQEEKDRKLSILAESIKASQKISEAPVRKTQLAFVDSMVKPPR 564
            .||..:....:|.|:|||::||..||::.:|..|..:| :|...::..:|:.::|:|:|.|||||
Zfish   463 CQRDFKHAAPQEYESWRELYLRLHEEREERLRKLTMNI-SSAHANKPKLRQVKMAYVNSAVKPPR 526

  Fly   565 SVQRKQEQYGTKGKLIAT----PAARV-----------------AALSSVTPNAAKVGDARLRVL 608
            .|:|:||::|||....:|    |:|::                 ::.||..|.::....|.....
Zfish   527 DVRRRQEKFGTKDGSFSTSAAPPSAKIRPATNYSIQSKPSDGGQSSFSSPAPESSSRSSAPSSAA 591

  Fly   609 A-AARDTAQVGAGPARSKKAPLMAKTLQFMRGR 640
            . :|||..||      .|.||:||||::..:.|
Zfish   592 GHSARDKPQV------KKIAPMMAKTIKAFKNR 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EloA	NP_732846.1	Med26	30..79	CDD:462573	26/50 (52%)
		Elongin_A	455..552	CDD:462026	39/96 (41%)
eloa	NP_998620.1	TFIIS_I	2..75	CDD:238107	31/73 (42%)
		Elongin_A	418..516	CDD:462026	39/98 (40%)