Protein Alignment EloA and Eloa

DIOPT Version :10

• Sequence 1: NP_732846.1
• Gene: EloA / 42749
• FlyBaseID: FBgn0039066
• Length: 643
• Species: Drosophila melanogaster
• Sequence 2: XP_063143264.1
• Gene: Eloa / 25562
• RGDID: 3827
• Length: 856
• Species: Rattus norvegicus
• Alignment Length: 787
• Identity: 216/787 - (27%)
• Similarity: 328/787 - (41%)
• Gaps: 193/787 - (24%)

  Fly     1 MASTSNLLDVVRHYQRSIEKHGEDEQRLLHCITKLFNLPIKFEHLQETGIGKTVNALRKISGEVG 65
            ||:.| .|.||...|..:..: .|.::||..:.||..|||..:.|.|||:|||||:.|| ..:||
  Rat    62 MAAES-ALQVVEKLQARLAAN-PDPKKLLKYLKKLSVLPITVDILVETGVGKTVNSFRK-HEQVG 123

  Fly    66 VAAKTLVTKWKAMVAKEDPSIASTPTAIHNE------EDSGKTKSSDEDPDQENKG-GN-----S 118
            ..|:.||.:||.:|          |...:||      |.|...|...:.|.||.:. ||     .
  Rat   124 NFARDLVAQWKKLV----------PVERNNEAEDQDFEKSNSRKRPRDVPQQEEEAEGNYQESWQ 178

  Fly   119 SSGEDLNTSKHK-SKHAKSTKHERSSSSRSHSKSRSDSDKK-HK--------------------- 160
            :||....:.:|: .||.|..:.||.... :|...|.|..|: ||
  Rat   179 ASGSQPYSPEHRQKKHRKLPELERPHKV-AHGHERRDERKRCHKVSPPYSSDPESSDYGHVQSPP 242

  Fly   161 -SSRH----DKSKDRDKDRE----GQKEAKEHKEKKSN-------GEHKSKDSSKSSSSHKSSKS 209
             ||.|    |.|:..:.|:|    ..|..|.|.....:       |||:.|.:...:..||||..
  Rat   243 PSSPHQMYTDLSRSPEMDQEPIVSHPKPGKVHSNTFQDRLGVSHLGEHQGKGAVSQNKPHKSSHK 307

  Fly   210 ES----------------HKSEHTKSKHE----------KDKTSHSELKEVKDK---SSKHKSSS 245
            |.                .||....||.|          |:|...|.:|:.||:   |.|.|.|.
  Rat   308 EKRPVDARGDEKSSVMGREKSHKASSKEESRRLLSEDSAKEKLPSSVVKKEKDREGNSLKKKLSP 372

  Fly   246 S--KSSKRSHSPPRHEEESQKAKIPKVKSKSEEDSADGFDSSMGAN------FDDVLGLLNIPIS 302
            :  .:|......|:|::..      |:||...:.|.|..||..|..      .|.|...|.....
  Rat   373 ALDVASDNHFKKPKHKDSE------KIKSDKNKQSVDSVDSGRGTGDPLPRAKDKVPNNLKAQEG 431

  Fly   303 SKKSSSNSKSKFVAKPTAAPS-----------------SSALSAPTTAGSSKEALSTS------- 343
            ..:::|:.||     |.:.|.                 .|.||........|:.:.||
  Rat   432 KVRTNSDRKS-----PGSLPKVEEMDMDDEFEQPTMSFESYLSYDQPRKKKKKVVKTSGTALGEK 491

  Fly   344 ------SRPTSKKPELLASTAKL----------------EPLDPNIA----------LELPTISN 376
                  |:.|||.   |.|..||                ||..|...          :.||.|..
  Rat   492 GLKKKDSKSTSKN---LNSAQKLPKVNENKSDKLQPAGAEPTRPRKVPTDVLPALPDIPLPAIQT 553

  Fly   377 NYKPMPLNQTVMDVVFNQGGSHKAQASRYFNESEALAQGISSKTMRTK--IYSGVRTGQILQVPS 439
            ||:|:|..:.:        .|.:.:...:.:..|....|.:.:.|.:|  :|||.:...:.::.:
  Rat   554 NYRPLPSLELI--------SSFQPKRKAFSSPQEEEEAGFTGRRMNSKMQVYSGSKCAYLPKMMT 610

  Fly   440 LFDLCTRVLQKNIDALEYTGGVPFEVLRPVLERATPQQLLNFEEYNPYLMDDSDVLWQQHVQRHC 504
            |...|.|||:.|||::...||||:.||.|||||.||.||...||.|..|::::|.||:.|..|..
  Rat   611 LHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEECNHVLIEETDQLWKVHCHRDF 675

  Fly   505 RSQRREEMETWREMFLRCQEEKDRKLSILAESIKASQKISEAPVRKTQLAFVDSMVKPPRSVQRK 569
            :.:|.||.|:||||:||.|:.::::|.:|..:|: |...::...|:.::|||:|:.||||.|:|:
  Rat   676 KEERPEEYESWREMYLRLQDAREQRLRLLTNNIR-SAHANKPKGRQAKMAFVNSVAKPPRDVRRR 739

  Fly   570 QEQYGTKG-----KLIATPAARVAALSSVTPNAAKVGDARLRVLAAARDTAQVGAGPARSKKAPL 629
            ||::||.|     |:...||......|.|     ...::.....::..:.|..|...:.:..||:
  Rat   740 QEKFGTGGAAVPEKVRIKPAPYTTGSSHV-----PASNSSSSFHSSPEELAYEGPSTSSAHLAPV 799

  Fly   630 MAKTLQF 636
            .:.::.:
  Rat   800 ASSSVSY 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EloA	NP_732846.1	Med26	30..79	CDD:462573	23/48 (48%)
		Elongin_A	455..552	CDD:462026	40/96 (42%)
Eloa	XP_063143264.1	None